Greenovation Biotech Gmbh

Andreas Nechansky

Manfred Schuster

Gilbert Gorr

Wolfgang Jost

Ralf Kircheis

The present invention relates to an antibody preparation comprising modified antibodies of an animal or derivatives or fragments thereof, specific for an antigen, characterized in that the antibodies or derivatives or fragments thereof comprise an N-glycan structure free of fucose and xylose, and at least 90%, preferably at least 95%, more preferred at least 99%, most preferred at least 100% of the modified antibodies, derivatives or fragments thereof lack a C-terminal lysine residue.

Glyco-engineered antibodies

The present invention relates to an antibody preparation comprising modified antibodies of an animal or derivatives or fragments thereof, specific for an antigen, characterized in that &#x2022; the antibodies or derivatives or fragments thereof comprise an N-glycan structure free of fucose and xylose, and &#x2022; at least 90%, preferably at least 95%, more preferred at least 99%, most preferred at least 100% of the modified antibodies, derivatives or fragments thereof lack a C-terminal lysine residue.

Growing community of inventors

Oberwaltersdorf, Austria

Andreas Nechansky