Multichannel Systems Mcs Gmbh

Unipix Sàrl

Andreas Möller

Philippe Renaud

Ulrich Egert

Kathrin Banach

Daniel Bertrand

Karl-Heinz Boven

The invention is achieved by a volumetric displacement calibration device () configured to be able to adapt at least one suction system (), comprising a tip (), having a volume VP, connected to a shaft () comprising a volume change mechanism (). The device () comprises at least one main chamber () and one reference chamber (), connected by a conduct () and a valve () to said main chamber () and at least one first pressure sensor () connected to said main chamber (). The device () comprises also a second pressure sensor () connected to said reference chamber (). The pressure sensors and calculation means allow to calculate an internal volume Vo, being the sum of the volume VP of said aspiration tip (), the volume () of the shaft () when the volume change mechanism () is down. The invention is also achieved by a system () comprising the device () and at least one suction system (-) adapted to said device (). The invention relates also to a calibration method of a volumetric fluid handling system () and comprising successive steps (a-m) to determine said volume Vo.

Liquid handling calibration device and associated method of calibration

In a method for determining the influence of a test substance on the heart activity of a vertebrate the following steps are performed:

Method for determining the influence of a test substance on the heart activity of a vertebrate

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Tübingen, Germany

Andreas Möller