Dragerwerk Aktiengesellschaft

Drager Sicherheitstechnik Gmbh

Andreas Manns

Thomas Wuske

Rainer Polzius

Horst Rabenecker

Philip-Michael Formica

Klaus P Rindt

Andreas Behnke

Kerstin Wex

Berthold Hock

Sabine Pullen

Sabine Grantz

A test strip for the immunochemical detection of substances after sampling from surfaces, with a conjugate zone (,) located between an eluent application zone (,) at one end of the test strip and a reaction zone (,) at the opposite end, the zones being in liquid connection with one another. A section of the test strip in the area including the eluent application zone and the reaction zone is used to wipe off the surface and as a sampling zone (,). The eluent application zone may be used as a sampling zone. The test strip is connected to a preferably flexurally rigid test strip holder (,), which does not cover the sampling zone (,).

Method of using a test strip for the immunochemical detection of substances

A device is provided for taking swab samples and sample dilution. The device has a plug made of a porous, absorbent material, which projects from a sleeve and is used to take a swab sample. The plug is located in one end of the sleeve. A piston, which can be moved in the sleeve by means of a piston rod, is located in the other end of the sleeve. A closure, which can be opened by means of pressure, is located between the piston and the plug, so that a liquid arranged between the piston and the plug moves through the closure to the plug and wets same on actuation of the piston rod.

Device for taking swab samples and sample dilution

A process for enriching substance emissions released from an object in the form of gases, vapors or aerosols, wherein the substance emissions are fed to an adsorption layer by diffusion or penetration and are enriched in the adsorption layer. The substance emission of an object is selectively detected according to the present invention by the adsorption layer being fixed on the surface of the object emitting pollutant, which surface is to be analyzed, by means of an adhesive tape projecting over the adsorption layer on all sides to offer adhesive surfaces for application to the object and to hermetically seal the adsorption layer against the ambient air. A nondestructive adsorption system is also provided, with direct or immediately following analysis for the rapid qualitative and/or quantitative determination of pollutants (e.g., gases, vapors, dusts) by means of a chemical or biological reaction, in which, e.g., specific biomolecules for selectively converting or selectively binding the collected or enriched pollutants and a system for displaying or identifying this conversion and/or binding are used.

Process and device for enriching gas, vapor and/or aerosol emissions

Highly selective monoclonal antibodies for pyrethrins and pyrethroids which, in their function as pesticides, contain a phenoxybenzyl and/or a cyclopropane component. The number of pyrethroids which can be selectively detected is increased and the possibility of differentiating among the various pyrethrins, pyrethroids and their metabolites is possible. An easy-to-use test kit detects pyrethrins and pyrethroids. A conjugate of a metabolite of the pyrethrins/pyrethroids (especially permethric acid or phenoxybenzoic acid) is coupled as hapten to a carrier protein to obtain the immunogen, which is used for immunization and for the subsequent cloning of suitable hybridomas.

Monoclonal antibodies for the detection of pyrethroids and a process for

A unitary collection and displacement immunoassay device for determining a toxic substance adhered to aerosols in the air is provided. The device comprises an elongated body having proximal and distal ends and encloses a space defining a collection chamber, a reaction chamber and a measurement chamber, each chamber separated by a liquid flow barrier which delays liquid transport between chambers until a vacuum source is applied to the distal end of the test device to pull liquid into the next chamber. The collection chamber contains a solution for solubilizing the toxic substance from the aerosols and a semi-permeable means for separating the solubilized toxic substance from the aerosols. The reaction chamber contains a labelled immunoreactant bound to a solid phase carrier material. The labelled reagent can be displaced by the solubilized toxic substance. The measurement chamber contains a color generating system which reacts with displaced labelled reagent to produce a colored product in proportion to the concentration of the toxic substance.

Reaction vessel for immunological analysis of aerosols

The present invention pertains to a process for determining an analyte, especially a low-molecular-weight pollutant in a sample. It is carried out by partially dipping into the sample a test strip, on which antibodies which are specific for the analyte and to which in turn a tracer is bound, are immobilized. During the capillary migration of the sample through the test strip, the analyte partially displaces the tracer. The tracer that has remained on the antibody is subsequently visualized by, e.g., dyeing. The intensity of the dyeing is an indicator of the amount of analyte detected.

Growing community of inventors

Lubeck, Germany

Andreas Manns