Boehringer Ingelheim International Gmbh

Morphosys Ag

Prothena Biosciences Limited

Andreas Langer

Patrick Garidel

Stefan Bassarab

Markus Hemminger

Ingo Michael Presser

Alexander Bauer

Nicole Denkinger

Hans-Joachim Kern

Michael Grundman

Bodo Brocks

Martin Hessling

Daniel Weinfurtner

Hans-Hoachim Kern

Udo Heinzelmann

Juergen Weber

The present disclosure describes a pharmaceutical formulation of an anti-CD19 antibody.

Anti-CD19 antibody formulations

The invention provides antibody formulations and methods useful for prophylaxis or treatment of synucleinopathies, including Parkinson's disease.

Antibody formulations and methods

Double chamber container for holding and combining, e.g., a lyophilizate and a liquid reconstitution medium, comprising

Dual chamber container for lyophilization, process for the filling up and use thereof

A double chamber container for holding and combining a solid lyophilizate and a liquid reconstituting medium, comprising a cylindrical body with a closure at each of the two ends, an upper displaceable closure at the reconstituting medium end, and a lower closure at the lyophilizate end, a separating stopper that can be pushed in the cylindrical body and act as a seal between the upper chamber and the lower chamber, and a bypass arranged underneath the separating stopper, with a length L that is preferably greater than the height H of the separating stopper, wherein at the upper end in the wall of the cylindrical body or in the separating stopper means are provided that allow partial connection of the interior of the cylindrical body to the environment during the lyophilization.

Dual chamber container and process for its filling up

The present invention relates to an apparatus for determining the shear sensitivity of particles in solutions and methods of determining the respective shear velocities or the respective shear stress.

Apparatus for quantifying shear stress on a formulation comprising biomolecules

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Maselheim, Germany

Andreas Langer