University of Texas System

Inex Pharmaceuticals Corporation

Hana Biosciences, Inc.

Other

Indiana University

Sloan-kettering Institute for Cancer Research

Talon Therapeutics, Inc.

Andreas H Sarris

Murray S Webb

Patricia M Logan

Clive T R Burge

Fernando Cabanillas

James H Goldie

Lawrence D Mayer

Thomas D Madden

Hal E Broxmeyer

Sean C Semple

Sandra K Klimuk

Quet F Ahkong

Jeff V Ravetch

Clive T Burge

This invention provides methods for treating neoplasias in a mammal. In particular, the invention provides methods for treating various types of lymphomas, including relapsed forms of non-Hodgkin's Lymphoma. These methods involve the administration of liposome-encapsulated vinca alkaloids, e.g., vincristine, to a mammal with a lymphoma.

Compositions and methods for treating lymphoma

This invention provides compositions and methods for treating neoplasias in a mammal. In particular, the invention provides liposome-encapsulated vinca alkaloids, e.g., vinorelbine, and methods of treating a mammal using such compositions.

Compositions and methods for treating cancer

The present invention discloses the correct processing of IP-10, a myelosuppressive protein produced by certain cells such as keratinocytes, monocytes and human endothelial cells upon stimulation by .gamma.-interferon. Also disclosed is a method of treating human cancer patients by applying IP-10 in a pharmaceutical composition in conjunction with certain antineoplastic agents.

Methods and compositions incorporating IP-10

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Houston, TX, United States of America

Andreas H Sarris