Boehringer Ingelheim International Gmbh

Andreas Gschwind

Marie-Ange Buyse

Erik Depla

Joachim Boucneau

Rene Georg Ott

Pascal Merchiers

Frederik Stevenaert

Eric Borges

Bispecifc binding molecules binding to both VEGF and Ang2, preferably in the form of immunoglobulin single variable domains like VHHs and domain antibodies, pharmaceutical compositions containing the same and their use in the treatment of diseases that are associated with VEGF- and/or Ang2-mediated effects on angiogenesis are disclosed. Further, nucleic acids encoding bispecific binding molecules, host cells and methods for preparing same are also described.

Bispecific binding molecules binding to VEGF and Ang2

Bispecific binding molecules binding to both VEGF and Ang2, preferably in the form of immunoglobulin single variable domains like VHHs and domain antibodies, pharmaceutical compositions containing the same and their use in the treatment of diseases that are associated with VEGF- and/or Ang2-mediated effects on angiogenesis are disclosed. Further, nucleic acids encoding bispecific binding molecules, host cells and methods for preparing same are also described.

Bispecific binding molecules binding to VEGF and ANG2

Growing community of inventors

Ingelheim am Rhein, Germany

Andreas Gschwind