Other

Forest Laboratories Holdings Limited

Richter Gedeon Nyrt.

Ironwood Pharmaceuticals, Inc.

Andreas Grill

Mark G Currie

Angelika Fretzen

Rahul Surana

Anil Chhettry

Ahmad Hashash

Ritesh Sanghvi

Haijian Zhu

Xiangmin Liao

Hiajian (Jim) Zhu

Matthew Ronsheim

Yun Mo

Matthew Miller

Joseph Stainkamp

Mohammad Mafruhul Bari

Mahendra Dedihiya

The present invention is directed to stable linaclotide compositions and methods of treating gastrointestinal disorders in patients in need thereof by providing the stable linaclotide compositions.

Linaclotide compositions

The present invention relates to novel crystalline forms of carbamoyl-cyclohexane derivatives and, more particularly, to novel co-crystalline forms of trans-1{4-[2-[4-(2,3-dichlorophenyl-piperazin-1-yl]-ethyl]-cyclohexyl}-3,3-dimethyl urea hydrochloride and an acid such as fumaric acid. Processes for preparing these forms, compositions containing these forms, and methods of use thereof are also described.

Crystalline form of carbamoyl-cyclohexane derivatives

The present invention relates to novel solvate and crystalline forms of carbamoyl-cyclohexane derivatives and, more particularly, to novel solvate and crystalline forms of trans-1{4-[2-[4-(2,3-dichlorophenyl)-piperazin-1-yl]-ethyl]-cyclohexyl}-3,3-dimethyl-urea hydrochloride. Processes for the preparation of these forms, compositions containing these forms, and methods of use thereof are also described.

Solvate and crystalline forms of carbamoyl-cyclohexane derivatives

The present invention relates to crystalline forms of linaclotide, as well as to various methods and processes for the preparation and use of the crystalline forms.

Crystalline form of linaclotide

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Hauppauge, NY, United States of America

Andreas Grill