Biotronik Se Co. Kg

Albert-ludwigs-universitat Freiburg

Andreas Bunge

Gerald Urban

Hoc Khiem Trieu

Henning Ebert

Sven Bode

Sarah Biela

Olaf Skerl

Michael Bergmann

Loic Ledernez

Joerg Naehring

Josef Horak

A sensor system detects a presence or concentration of an analyte in a medium. The sensor system contains a sensor having a sensor head with a chamber. The sensor head has a permeable area through which the analyte can pass into the chamber when the sensor head contacts the medium. A cross-linked hydrogel fills the chamber, the hydrogel is configured to undergo a change in volume when contacting the analyte passed into the chamber which leads to a change in pressure in the chamber. A pressure sensor is configured to measure the pressure in the chamber for detecting the presence or concentration of the analyte.

Sensor system, method and cross-linked hydrogel for detecting the presence or concentration of analytes

A method for coating a medical implant applies at least one coating to at least one surface of the implant by plasma polymerization. The implant has pores sized in the nanometer range. The method stabilizes the pores. The plasma polymerization is conducted in the presence of a coating gas and oxygen. A coating parameter can be selected so that a rough surface of the implant is coated. An implant includes a membrane having pores sized in the nanometer range. A surface of the implant is at least partially coated with a plasma polymer. The interior of the pores is uncoated.

Method for coating a medical implant

Embodiments of the invention include a biosensor, such as an implantable biosensor, that includes a sensor material sensitive to at least one analyte in a pressure measurement chamber coupled to a pressure sensor. In embodiments of the invention, a pressure prevailing in the pressure measurement chamber may be determined by the pressure sensor. The sensor material is coupled in the pressure measurement chamber to a compensation material, which includes a relationship between a temperature and a volume of the pressure. The relationship is opposite to a temperature-dependent change in pressure or volume of the sensor material and at least partially compensates for a cross-sensitivity-induced change in volume of the sensor material.

Cross-sensitivity-compensated biosensor

The invention relates to a medical sensor system () for detecting a feature (), such as an analyte, in a human or animal body. The system () includes at least one sensor () having a reservoir () with a cap () designed as a controllable organic membrane (), wherein (for example) application of a voltage of a particular magnitude, or application of a voltage for a particular time, effects a change in the permeability of the membrane ().

Medical sensor system for detecting a feature in a body

A medical sensor system (') for detecting at least one characteristic () of an human and/or animal body has a sensor (), a first characteristic carrier (), and a characteristic carrier receptor (). The first characteristic carrier () differs, in terms of at least one characteristic parameter, from a second characteristic carrier () which is present at least at the time of detection. The sensor () is preferably located in vivo at the time of detection of the at least one characteristic.

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Andreas Bunge