Dr. Karl Thomae Gmbh

Henkel Kommanditgesellschaft Auf Aktien

Boehringer Ingelheim Gmbh

Dr. Karl Tomae Gmbh

Andreas Bomhard

Norbert Hauel

Berthold Narr

Joachim Heider

Klaus Reinhold Noll

Manfred Psiorz

Walter Kobinger

Christian Lillie

Willi Diederen

Jacques Van Meel

Georg Knuebel

Thomas Markert

Wolfgang Wienen

Manfred Reiffen

Michael Entzeroth

Ulf-Armin Schaper

Jurgen Dammgen

Theo Stalberg

Armin Heckel

Volkhard Austel

Uwe Joerg Ries

Wolfgang Grell

Process for the production of 8.alpha., 12-oxido-13,

Process for the production of 8 .alpha.,

The invention relates to benzimidazoles of the formula ##STR1## in which R.sub.1 to R.sub.2 are as defined in claim 1, 1 and 3 isomer mixtures thereof and addition salts thereof which have valuable properties. In particular, the novel compounds are angiotensin II antagonists.

Benzimidazoles and medicaments containing these compounds

A phenylalkyl derivative of the formula ##STR1## wherein R.sub.a to R.sub.f, A and B are substituents and n is the number 0 or 1. These phenylalkyl derivatives possess angiotensin antagonist activity.

Phenylalkyl derivatives, with pharmaceutical activity

Disclosed are new cyclic amine derivatives of the formula I ##STR1## wherein the substituents are defined in the specification. These compounds are useful as for treating sinus tachycardia.

Cyclic amine derivatives, pharmaceutical compositions containing these

The present invention relates to new heteroaromatic amine derivatives of general formula ##STR1## wherein the substituents are defined hereinbelow, which have valuable pharmacological properties, particularly a heart rate lowering activity and a positive inotropic activity.

Heteroaromatic amine derivatives

Heteroaromatic amine derivatives, pharmaceutical compositions containing

The present invention relates to new naphthyl derivatives of general formula ##STR1## wherein N represents the number 1 or 2,

Naphthyl derivatives, pharmaceutical compositions containing these

The invention relates to new imidazo-benzoxazinones of formula ##STR1## wherein the substituents are defined herein below, which compounds are useful in the treatment of cardiovascular disorders.

Imidazo-benzoxazinones, the preparation thereof and pharmaceutical

The invention relates to new heteroaromatic amine derivatives of formula ##STR1## wherein A represents a --CH.sub.2 --CH.sub.2 --, --CH.dbd.CH--or ##STR2## group and B represents a methylene, carbonyl or thiocarbonyl group or A represents a --CO--CO or ##STR3## group and B represents a methylene group, in which the carbon atom marked x is linked to the phenyl nucleus,

(2H)-3-benzazepin-2-ones, their pharmaceutical compositions and their

The invention relates to new imidazo derivatives of the formula ##STR1## wherein 'A-D and R.sup.1 -R.sup.3 are as defined in the specification'. The new compounds have valuable pharmacological properties, particularly antithrombotic and cardiovascular properties such as a cardiotonic activity and/or an effect on blood pressure, and can be prepared using methods known per se.

Imidazo[1,2a]pyridines and their use as cardiotonic agents

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Duesseldorf, Germany

Andreas Bomhard