Sosei R&d Ltd.

Andrea Walmsley

Andrew Douglas Baxter

Compounds that may have anti-inflammatory activity are of general formula (I); wherein X, is H or COR, and Xis H or CORbut X, and Xare not both H; Rand Rare the same or different and are each Calkyl substituted with R, or a four to seven-membered ring which can be optionally substituted with Rand can contain one or more additional heteroatoms selected from O, S(O)and NR; is Ris F, CF, OR, NRRO, S(O)R; R, Rand Rare the same or different and are each H or Calkyl optionally substituted with R, or NRRis a Cheterocycloalkyl ring containing one or more heteroatoms selected from O, NRand S(O); each n is 0-2; Ris Calkyl; Ris as defined for Ror Calkyl optionally substituted with Ror halogen; and Ris H or Calkyl; or a salt, solvate or hydrate thereof. 

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Essex, United Kingdom

Andrea Walmsley