Bam Bundesanstalt Fuer Materialforschung Und-pruefung

Bam Bundesanstalt Fur Materialforschung Und-prufung

Bundesrepublik Deutschland, Vertreten Durch Das Bundesministerium Fuer Wirtschaft Und Technologie, Dieses Vertreten Durch Den Praesidenten Der Bam, Bundesanstalt Fuer Materialforschung Und-pruefung

Bundesrepublik Deutschland Vertreten Durch Das Bundesministerium Fur Wirtschaft Und Technologie

Andrea Spitzer

Georg Berger

Renate Gildenhaar

Christian Jäger

Jutta Pauli

Jens Guenster

Jens Günster

Heidi Marx

Dagmar Nicolaides

A sinterable and/or fusible ceramic mass is disclosed, having a long-term stable compound of crystalline phases of apatite, wollastonite, titanite and optionally cristobalite, which is stabilized by a glass phase, and a production process therefor. The ceramic mass can be obtained by sintering a mixture comprising at least the constituents SiO, CaO, PO, MgO, CaFand TiO, on their own or in combination with at least one alkali oxide, the alkali oxide being chosen from NaOand KO. The invention further relates to uses of the sintered material in the form of shaped articles for strengthening, cleaning, roughening or polishing surfaces of medical implants or as a final prosthesis.

Sinterable and/or fusible ceramic mass, production and use thereof

The present invention relates to an X-ray amorphous-crystalline material with high solubility which can be used as a bioactive bone replacement material and as a substrate material in biotechnology. The new material comprising crystalline and X-ray amorphous phases is characterized in that according toP-NMR measurements, it contains Q-groups of orthophosphate and Q-groups of diphosphate, the orthophosphates or Q-groups making up 70 to 99.9% by weight relative to the total phosphorus content of the finished material and the diphosphates or Q-groups making up 0.1 to 30% by weight relative to the total phosphorus content of the finished material, and that according to X-ray diffractometric measurements and relative to the total weight of the finished material, 30 to 99.9% by weight of a main crystal phase consisting of CaKNa(PO), where x=0.1 to 0.9, is contained in the bone replacement material and 0.1 to 20% by weight of a substance selected from the group consisting of NaCaPO, KCaPO, CaPOand mixtures thereof is contained as a secondary crystal phase, the X-ray amorphous phases contained besides the main crystal phase jointly making up 0.1 to 70% by weight relative to the total weight of the finished material.

Bone replacement material comprising crystalline phases

The present invention relates to an X-ray amorphous-crystalline material with high solubility which can be used as a bioactive bone replacement material and as a substrate material in biotechnology. The new material comprising crystalline and X-ray amorphous phases is characterized in that according toP-NMR measurements, it contains Q-groups of orthophosphate and Q-groups of diphosphate, the ortho-phosphates or Q-groups making up 70 to 99.9% by weight relative to the total phosphorus content of the finished material and the diphosphates or Q-groups making up 0.1 to 30% by weight relative to the total phosphorus content of the finished material, and that according to X-ray diffractometric measurements and relative to the total weight of the finished material, 30 to 99.9% by weight of a main crystal phase consisting of CaKNa(PO), where x=0.1 to 0.9, is contained in the bone replacement material and 0.1 to 20% by weight of a substance selected from the group consisting of NaCaPO, KCaPO, CaPOand mixtures thereof is contained as a secondary crystal phase, the X-ray amorphous phases contained besides the main crystal phase jointly making up 0.1 to 70% by weight relative to the total weight of the finished material.

Bone replacement material comprising crystalline and X-ray amorphous phases

The present invention relates to a material with orthophosphate and having a high solubility which can be used as a bioactive bone replacement material and as a substrate material in biotechnology. According toP-NMR measurements, the new material comprises Q-groups of orthophosphate and Q-groups of diphosphate, the orthophosphates or Q-groups making up 65 to 99.9% by weight relative to the total phosphorus content of the finished material and the diphosphates or Q-groups making up 0.1 to 35% by weight relative to the total phosphorus content of the finished material, and wherein according to X-ray diffractometric measurements and relative to the total weight of the finished material, 35 to 99.9% by weight of a main crystal phase consisting of CaNa(PO), CaK(PO), mixtures thereof or mixed crystals according to the general formula CaKNa(PO), where x=0 to 1, is contained in the bone replacement material and 0.1 to 25% by weight of a substance selected from the group consisting of NaCaPO, KCaPO, CaPOand mixtures thereof is contained as a secondary crystal phase, and the X-ray amorphous phases contained besides the main crystal phase jointly make up 0.1 to 65% by weight.

Bone replacement material with orthophosphate

The present invention relates to a glass used as a sintering aid for a resorbable molded body containing calcium phosphate as well as to a method for manufacturing said molded body. According to the invention, the material is &#x3b2;-tricalcium phosphate and the glass has a chemical composition of 68&#x2013;78% by weight SiO, 5&#x2013;12% by weight MgO and 12&#x2013;27% by weight NaO. The aforesaid molded body is manufactured by melting said glass, grinding it until a grain size Dof 0.7&#x2013;2 &#x3bc;m is achieved and mixing it with &#x3b2;-tricalcium phosphate having a grain size Dof 1&#x2013;7.5 &#x3bc;m, giving the mixture the desired shape and producing the molded body by sintering said mixture at between 1,150 and 1,350&#xb0; C., wherein the grain size of &#x3b2;-TCP must not be smaller than that of the glass.

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Berlin, Germany

Andrea Spitzer