Other

Jarrow Formulas, Inc.

Universitat Heidelberg

Andrea Savarino

Umberto Dianzani

Ahmed Taha Ayoub

Marina Lusic

Iart Luca Shytaj

Peptides representing sequences from region 45-74 of the human CD38 leukocyte surface antigen (SEQ ID NO:1) are provided which may be used to inhibit or prevent transmission or replication of the HIV virus. The peptides have from 13 to 30 amino acids and include the amino acid sequence GPGTTK (SEQ ID NO:18) for topical application to inhibit or prevent transmission of the HIV virus.

Antiviral compositions comprising a multiple branched peptide construct containing human CD38 leukocyte surface antigen polypeptides

Microbicidal compositions comprising human CD38 polypeptides derived from the extracellular membrane-proximal region

Compositions containing anti-HIV peptides and methods for use

The present invention relates to a drug combination capable of conferring therapeutic benefits in the treatment of both AIDS and malaria. In particular, it relates to a drug combination including at least one quinolinic antimalarial compound such as chloroquine or hydroxychloroquine, and at least one inhibitor of the Human Immunodeficiency Virus (HIV) protease enzyme. This drug combination is capable of inhibiting the replication of both HIV andsp. It also relates to the direct antimalarial effects of the HIV PIs.

Methods for treatment of HIV or malaria using combinations of chloroquine and protease inhibitors

Growing community of inventors

Vinovo, Italy

Andrea Savarino