Basf Se Corporation

Evolva Sa

Andrea Molt

Oskar Zelder

Klaus Ditrich

Michael Breuer

Holger Hartmann

Birgit Hoff

Hartwig Schroeder

Jakob Weber

Hartwig Schröder

Karsten Koerber

Stefan Haefner

Michael Naesby

Markus Schwab

Christophe Folly

Curt Aimé Friis Nielsen

Anaelle Hatsch

Rüdiger Reingrubber

Rüdiger Reingruber

Microorganisms and processes for the recombinant manufacture of clavine-type alkaloids such as cycloclavine, festuclavine, agroclavine, chanoclavine and chanoclavine aldehyde, as well as polypeptides, polynucleotides and vectors comprising such polynucleotides which can be applied in a method for the manufacture of clavine-type alkaloids are provided.

Genes and processes for the production of clavine-type alkaloids

The invention pertains to the field of production of natural products and, in particular, in the field of production of cornexistin and hydroxycornexistin. It provides polynucleotides encoding polypeptides involved in the biosynthesis of cornexistin and hydroxycornexistin as well as vectors and recombinant microorganisms comprising such polynucleotides. Also provided are methods for the production of natural products, in particular methods for the production of cornexistin and hydroxycornexistin, using such polynucleotides and polypeptides encoded therein, as well as vectors and recombinant microorganisms comprising such polynucleotides and polypeptides.

Gene cluster for biosynthesis of cornexistin and hydroxycornexistin

The invention pertains to the field of production of natural products and, in particular, in the field of production of cornexistin and hydroxycornexistin. It provides polynucleotides encoding polypeptides involved in the biosynthesis of cornexistin and hydroxycornexistin as well as vectors and recombinant microorganisms comprising such polynucleotides. Also provided are methods for the production of natural products, in particular methods for the production of cornexistin and hydroxycornexistin, using such polynucleotides and polpeptides encoded therein, as well as vectors and recombinant microorganisms comprising such polynucleotides and polypeptides.

Growing community of inventors

Weinheim, Germany

Andrea Molt