Evonik Operations Gmbh

Evonik Roehm Gmbh

Evonik Corporation

Windhab, Norbert

Brücher, Christoph

Andrea Engel

Norbert Windhab

Melanie Liefke

Anne Benedikt

Peter Niepoth

Silko Grimm

Jessica Müller-Albers

Matthias Germer

Andreas Karau

Michael Damm

Kevin Burton

Julia Lyubina

Thomas Gottstein

Christoph Brücher

Paul Joseph Spencer

Tom Tice

Jens Daufenbach

Rima Jaber

Rüdiger Alexowsky

Maria Steinke

Juan Tome-Alcalde

Roland Brock

Verena Melk

Alexander Henrik Baron Van Asbeck

Susanne Ullrich

Steffen Kistner

Jürgen Dieker

Jochen Bodem

Jean-Luc Herbeaux

Rike Nabbefeld

Carsten Dentler

Maria Camilla Operti

David Fecher

Min Yang

A method of unambiguous identification and authentication of products for the purpose of better recognition of product forgeries and controlling product piracy, including applying to/into the product an identification substance admixture which contains paramagnetic phases or identifying a product which contains an identification substance admixture containing paramagnetic phases and has an ESR fingerprint spectrum that permits unambiguous identification of the product. Such an ESR fingerprint spectrum is easily measurable, but can be copied or forged only with difficulty. The method relates to an individualizable 'femto tag' for femto ledgers and forms an important interface for what are known as “Internet of Things” (IOT).

Unique identification and authentication of products

A composition may be used in treating or preventing a virus infection in a subject, wherein the virus is from the Paramyxoviridae family and wherein the composition includes an extract of black currants and bilberries. The composition may contain an extract from black currants and bilberries in a weight ratio in a range of from 0.5:1 to 1:0.5. The extract may be an alcoholic extract, such as a methanol extract. The composition may be administered to the subject 1 to 10 oral dosages of at least 80 mg anthocyanins each per day, preferably 3 to 6 oral dosages of at least 80 mg anthocyanins each per day. The subject may not have received a measles vaccination or have previously been exposed to the measles virus.

Preparations containing berry extracts for use in the prophylaxis and/or treatment of viral infections caused by Paramyxoviridae

A process can be used for preparing nanoparticles containing at least one bio-resorbable polyester. The nanoparticles are in the form of a powder with a Z-Average particle size Din the range of 1 to 450 nm, and with a polydispersity index PDI in the range of 0.01 to 0.5. The process involves emulsion-solvent extraction or emulsion-solvent evaporation, and application of ultrasonic sound.

Process for preparing nanoparticles in the form of a powder comprising a bio-resorbable polyester

A process can be used for preparing nano- or microparticles containing a carrier-polymer and a biologically active ingredient. The process is a solvent emulsion process involving an organic phase (OP) and an aqueous phase (AP) to form an emulsion. In the case of an oil-in-water emulsion (O/W), the organic phase (OP) contains the biologically active ingredient dissolved or dispersed therein. Alternatively, in the case of a water-in-oil emulsion (W/O), the aqueous phase (AP) contains the biologically active ingredient dissolved or dispersed therein. The organic phase (OP) is saturated with the salt-containing aqueous phase (AP) and vice versa.

Process for preparing nano-or microparticles comprising a carrier-polymer and one or more biologically active ingredients

A process prepares a polymer powder, with a D50 particle size from 40 to 200 &#x3bc;m and a Hausner factor of 1.25 or less, by freeze drying and subsequent loosening up of an aqueous polymer dispersion containing 15 to 50% by weight of a polymer. The polymer is polymerized from 10 to 30% by weight of methyl methacrylate, 50 to 70% by weight of methyl acrylate, and 5 to 15% by weight of methacrylic acid.

Process for preparing a polymer powder

A nanoparticle includes a core. The core includes a bio-resorbable polyester and a hydrophilic polymer. The hydrophilic polymer is a portion of the bio-resorbable polyester or a separate polymer. An acylated human lactoferrin-derived peptide is coated onto the core. The acylated human lactoferrin-derived peptide is a peptide with the amino acid sequence SEQ ID NO. 1: KCFQWQRNMRKVRGPPVSCIKR or an amino acid sequence, which does not differ by more than 8 amino acid positions from the sequence SEQ ID NO: 1. The N-terminus of the human lactoferrin-derived peptide is acylated with a C-monoacyl group.

Nanoparticle comprising a bio-resorbable polyester, a hydrophilic polymer and an acylated human lactoferrin-derived peptide

The present invention relates to a gastric retention active delivery system in the form of a coated capsule, which, in contrast to prior art delivery systems exhibiting relatively poor floating-properties, and thus requiring size expansion capability in order to securely delay passage through the pylorus, reliably stay afloat for several hours. This is achieved by combining pore forming components and flexible polymer components in the coating in suitable proportions. The present invention, further, relates to the use of gastric retention active delivery systems of the invention for the delivery of one or more water soluble active components A to a mammal.

Gastric retention active delivery systems

A process for preparing a powder, which includes one or more human coagulation factor proteins and a lactic acid polymer, involves mixing and dispersing a lactic acid polymer with a particle size din the range 0.1-2 &#x3bc;m and the one or more human coagulation factor proteins in water. The dispersion is dried, and the resulting dried mass is compressed. The resulting compressed dried mass is comminuted to a powder with a particle size din the range of more than 0.5 and up to 5 &#x3bc;m.

Process for preparing a powder comprising a human coagulation factor protein and a lactic acid polymer

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Birmingham, AL, United States of America

Andrea Engel