Alfasigma S.p.a.

Sofar S.p.a.

Lac2biome S.r.l.

Andrea Biffi

Walter Fiore

Ruggero Rossi

Silvia Salamina

Simone Guglielmetti

Silvia Balzaretti

Simone Domenico Guglielmetti

Compositions comprising a mixture comprising the bacterial strainMIMBb23sg or BbfIBS01 (DSM 32708), at least one or more bacterial strains selected from group A comprising the strainsBbIBS01 (DSM 33231),BbIBS02 (DSM 33232),subsp.BlIBS01 (DSM 33233) andLpIBS01 (DSM 33234) and, optionally, at least one further bacterial strain selected from a bacterial strainDG® (CNCM I-1572) and a bacterial strainLPC-S01™ (DSM 26760) and related method for the treatment of gastrointestinal diseases, disorders or symptoms, in particular functional gastrointestinal disorders, such as, for example irritable bowel syndrome (IBS) are described.

Bacterial strains, their compositions and their use for the treatment of gastrointestinal disorders

The present invention regards a composition based on bacteria belonging to thespecies for use in the treatment and/or in the prevention of a pathological condition of the female urogenital tract, preferably a pathological condition of the female genital tract, more preferably of the vagina, said pathological condition being caused by or related with a vaginal microbiota imbalance or for treating and/or preventing the symptoms related with said pathological condition.

Bacterial strains of thespecies for use, oral or topical, in the treatment of disorders of the female urogenital tract

The present invention relates to the use of probiotics to control the inflammatory process of the colon in subjects with structural modifications of the colon wall, preferably in subjects with diverticulosis, and affected by diverticular disease.

Probiotics for use in the treatment of diverticulosis and diverticular disease

The present invention relates to the use of a composition comprising bacteria to increase the intestinal production of butyric acid, folic acid or niacin and/or to decrease the intestinal production of succinic acid. Moreover, the present invention relates to the use of said composition for the treatment and/or prevention of an intestinal butyrate- and/or succinate-dependent pathological condition. In particular, for the treatment and/or the prevention of intestinal inflammation, diarrhoea, ulcerative colitis or intestinal colopathies.

Use of a composition comprising microorganisms to increase the intestinal production of butyric acid, folic acid or niacin and/or decrease the intestinal production of succinic acid

Compositions, food products, methods and systems for use in increasing the blood bioavailability of amino acids derived from proteins, preferably proteins of plant origin, comprising a mixture M comprising or, alternatively, consisting of at least one bacterial strain, preferablyDG&#xae; CNCM I-1572 and/orLPC-S01&#x2122; DSM 26760, and possibly. The compositions food products, methods and systems o the disclosure, can further comprise at least one protein, preferably proteins of plant origin, or a peptide or an amino acid, and in particular includes a food product comprising proteins, preferably of plant origin, and said mixture M of at least one bacterial strain.

Compositions comprising bacterial strains for use in increasing the bioavailability of amino acids derived from proteins, and related food product methods and systems

The present invention relates to the use of a composition based on bacteria and/or yeasts and/or other microorganisms, taken singularly or in combination, for the treatment of abdominal pain by administering to a patient suffering from Irritable Bowel Syndrome (IBS). In particular, the bacteria compriseDG strain deposited with the deposit number CNCMI 1572.

Medical use of probiotics

The present invention relates to a composition which comprises a mixture which comprises or, alternatively, consists of an extract (a) of a fruit of at least one plant of the genusand at least one ingredient (b) acceptable for pharmaceutical or food use and the use thereof in the prevention and/or treatment of diverticular disease or of a pathology deriving therefrom or correlated thereto.

Composition for use in the treatment of intestinal alterations

The present invention refers to exopolysaccharide molecules, conditioned media or compositions comprising said molecules or media. Moreover, the present invention refers to use of said exopolysaccharide molecules, conditioned media or compositions as prebiotic, preferably to boost immune system.

Exopolysaccharides and uses thereof

The present invention relates to a composition comprising probiotics, preferably based on bacteria, in particular of the genus, to be used for the purpose of preventing and/or treating the disorders affecting the skin, in particular inflammatory disorders, in particular autoinflammatory disorders of dermatological interest such as atopic dermatitis. Furthermore, the composition of the invention is useful for preventing and/or reducing the damage induced by UV radiation, in particular skin aging.

Composition based on probiotics and uses thereof

The present invention relates to a topical composition containing a probiotic and hyaluronic acid or a pharmaceutically acceptable salt thereof, for use in the treatment and/or prevention of inflammatory bowel disease.

Topical composition for use in the treatment of inflammatory bowel disease

The present invention relates to the use of probiotics, preferably one or more probiotic bacteria, to increase the absorption of proteins or the bioavailability thereof, preferably in individuals with increased protein and/or energy requirements, preferably elderly persons, children, pregnant women or athletes.

Use of probiotics for improving protein absorption

The present invention relates to the use of specific strains ofor of a composition comprising said strains for the prevention and/or treatment of a physiopathological condition related to/associated withinfection, preferably intestinal infections, or so-called CD-associated disease (CDAD) or CD infection (CDI).

Growing community of inventors

Urgnano, Italy

Andrea Biffi