Covis Pharma Gmbh

Sunovion Pharmaceuticals Inc.

Sumitomo Pharma America, Inc.

Andrea Bauer

Paul Mcglynn

Shahla Jamzad

Helgert Müller

Haitao Zhang

Michael Joseph Sizensky

Robert Joseph Prytko

Xiaoxia Chen

Ulrich Bildmann

Renate Engelstätter

Harold Scott Wilkinson

Kostas Saranteas

Nandkumar Nivritti Bhogle

This invention relates to a pharmaceutical aerosol product suitable for administration by oral or nasal inhalation and its use in the treatment of respiratory diseases, in particular in the treatment of children. The aerosol composition comprises ciclesonide, ethanol and either 1,1,1,2-tetrafluoroethane, or 1,1,1,2,3,3,3-heptafluoropropane.

Pharmaceutical aerosol product for administration by oral or nasal inhalation

This invention relates to a pharmaceutical aerosol product suitable for administration by oral or nasal inhalation and its use in the treatment of respiratory diseases, in particular in the treatment of children. The aerosol composition comprises ciclesonide, ethanol and either 1, 1, 1, 2-tetrafluoroethane, or 1, 1, 1, 2, 3, 3, 3-heptafluoropropane.

Provided are salts of (S)-(4,5-dihydro-7H-thieno[2,3-c]pyran-7-yl)-N-methylmethanamine and various of crystal forms thereof, and compositions, medicaments, pharmaceutically acceptable formulations thereof, and methods of making same. In addition, provided are compounds comprising specific particle size distributions of crystalline (S)-(4,5-dihydro-7H-thieno[2,3-c]pyran-7-yl)-N-methylmethanamine HCl and methods of making and modulating the particle size distributions.

Salts, crystal forms, and production methods thereof

The inventive subject matter relates to a pharmaceutical aerosol product suitable for administration by oral or nasal inhalation and its use in the treatment of respiratory diseases, in particular in the treatment of children.

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North Reading, MA, United States of America

Andrea Bauer