Sanofi

Sanofi Sa

C M Industries

Andre Hallot

Kathleen Biziere

Henri Demarne

Jean-Pierre Chambon

Paolo Carminati

Jean-Paul Kan

Jean N Vallat

Geard Barthelemy

The present invention relates to the compounds of formula ##STR1## in which X.sub.1 represents N or ##STR2## X.sub.2 represents N or ##STR3## provided that X.sub.1 and X.sub.2 are different from each other; R.sub.1 and R.sub.2 being --(CH.sub.2).sub.n OH wherein n is 1 to 4 or ##STR4## represents a saturated heterocycle with 5 or 6 groupings containing one nitrogen atom as heteroatom, substituted in 3 or 4 position for example by (CH.sub.2).sub.m OR.sub.6 where R.sub.6 is H or an acyl radical or an amido radical; to a process for preparing said compounds; and to the drugs containing said compounds active in particular on the central nervous system.

Pyridazine and pyrimidine compounds active on the central nervous system

The invention relates to compounds with a nitrogen-containing heterocyclic nucleus, of the general formula: ##STR1## in which: Ar represents a group ##STR2## or a naphthyl group optionally substituted by a halogen, A represents a heterocyclic nucleus chosen from the group consisting of the pyridine, pyrimidine and triazine nuclei, and

Compounds with a nitrogen-containing heterocyclic nucleus, and drugs in

Benzodiazepines of formula ##STR1## wherein R3 is methyl or ethyl and R4 is chlorine or fluorine are useful therapeutic agents for the treatment of neuropsychic disturbances.

Method of treating neuropsychic disturbances by benzodiazepine

This invention relates to triazolo-pyrimidine derivatives corresponding to the following formula: ##STR1## wherein X represents a 2-pyridyl, 3-pyridyl or 4-pyridyl nucleus optionally substituted by at least one straight-chained or branched C.sub.1-4 alkoxy or alkyl or a hydroxy or cyano group,

Triazolo-pyrimidine derivatives, a process for preparing them and their

The present invention relates to a process for preparing 2-(1-piperazinyl) pyrimidines of formula: ##STR1## in which one of the groups T and Q represents hydrogen, a hydroxyl or lower alkanoyloxy group, and the other represents hydrogen; and X represents:

2-(1-Piperazinyl) pyrimidines, their salts and pharmaceutical

The present invention relates to new derivatives of formula: ##STR1## in which: R.sub.3 denotes a halogen, preferably chlorine, or a nitro group,

1-Piperazinyl 4-phenylquinazoline compounds having antidepressant

The present invention relates to novel derivatives of 4-phenyl quinazoline of general formula: ##STR1## in which R.sub.2 is H or halogen or R.sub.1 is a hydroxyamino derivative of type ##STR2## in which at least R.sub.3 or R.sub.4 comprises an OH group or ##STR3## in which R.sub.5 comprises an OH group or ##STR4## it also relates to the drugs which may be used as minor tranquilizers, hypnotics and antiepileptics containing a product of formula (I).

Derivatives of 4-phenyl quinazoline active on the central nervous system

The invention relates to benzodiazepine compounds of the formula: ##STR1## wherein R.sub.5 is C.sub.1 -C.sub.4 alkyl, R.sub.3 is C.sub.1 -C.sub.4 alkyl, and R.sub.4 is selected from Cl and F, and medicaments containing such benzodizepine compounds.

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St. Gely Du Fesc, France

Andre Hallot