L'oreal

Andre Deflandre

Gerard Lang

Serge Forestier

Herve Richard

Alain LaGrange

Irena Beck

Jean R Maignan

Madeleine Leduc

Gerard Malle

Bernadette Luppi

Michel Dubois

Jean Cotteret

Jean F Grollier

Isabelle Hansenne

Claudine Moire

A photostable cosmetic filter composition for protecting human skin against UV radiation at wavelengths between 280 and 380 nm comprises, in a cosmetically acceptable support medium containing at least one oily phase, 1 to 3% by weight of a dibenzoylmethane derivative and at least 1% by weight of a substituted dialkylbenzalmalonate having formula I: ##STR1## R.sub.1 and R.sub.3 may be identical or different and represent H or a straight- or branched-chain C.sub.1 -C.sub.8 alkoxy radical. R.sub.2 and R.sub.4 represent a straight- or branched-chain C.sub.1 -C.sub.8 alkyl radical. The molar ratio of compound (I) to the dibenzoylmethane derivative is greater than or equal to 0.6.

Photostable cosmetic filter composition containing a UV-A filter and a

A photostable cosmetic filter composition for protecting human skin against UV radiation at wavelengths between 280 and 380 nm comprises, in a cosmetically acceptable support medium containing at least one oily phase, 1 to 3% by weight of a dibenzoylmethane derivative and at least 1% by weight of a substituted dialkylbenzalmalonate having formula I: ##STR1## R.sub.1 and R.sub.3 may be identical or different and represent H or a straight- or branched-chain C.sub.1 -C.sub.8 alkoxy radical.

Photostable cosmetic filter composition cotaining a UV-A filter and a

Photostable filtering cosmetic composition containing a UV-A filter and

The invention relates to a photostable screening cosmetic composition for protecting human skin against UV rays, comprising, in a cosmetically acceptable substrate containing at least one fatty phase, 1 to 3% by weight of 4-(1,1-dimethylethyl)-4'-methoxydibenzoylmethane and at least 4.5% by weight of p-methylbenzylidenecamphor, the weight ratio of p-methylbenzylidenecamphor to 4-(1,1-dimethyl-ethyl)-4'-methoxydibenzoylmethane being higher than or equal to 3. It also relates to a process for protecting the skin against UV radiation and to a process for stabilizing 4-(1,1-dimethylethyl)-4'-methoxydibenzoylmethane against UV radiation.

Photostable cosmetic composition containing a UV-A screen and a UV-B

A photostable cosmetic screening composition and process for protection of the human epidermis against UV rays of wavelengths between 280 and 380 nm, the composition having, in a cosmetically acceptable vehicle containing at least one fatty phase, 1 to 5% by weight of a dibenzoylmethane derivative and at least 1% by weight of an alkyl .beta.-.beta.-diphenylacrylate or .alpha.-cyano-.beta.-.beta.-diphenylacrylate of formula (I), the mole ratio of the compound of formula (I) to the dibenzoylmethane derivative being not less than 0.8.

Photostable cosmetic screening composition containing a UV-A screening

##STR1## A photostable filtering cosmetic composition for protecting the human epidermis against UV radiation comprises, in a cosmetically acceptable carrier containing at least one fatty phase, from 0.5 to 5% by weight of 4-(1,1-dimethylethyl)-4'-methoxy dibenzoylmethane and at least 0.5% by weight of a compound of formula (I) where R stands for an alkyl radical, the molar ratio of the compound of formula (I) to 4-(1,1-dimethylethyl)-4'-methoxy dibenzoylmethane being 0.8 or over.

Process for stabilizing 4-(1,1-dimethylethy)-4'methoxydibenzoyl-methane

The invention relates to the benzylcyclanone derivatives of formula: ##STR1## where R.sub.1 and R.sub.3 denote H, OH, linear or branched C.sub.1 -C.sub.8 alkyl or linear or branched C.sub.1 -C.sub.8 alkoxy, R.sub.2 and R.sub.4 represent H or OH, at least one of the two being OH, R.sub.5, R.sub.6, R.sub.7 and R.sub.8 represent H, C.sub.1 -C.sub.18 alkyl, aralkyl or aryl, it being possible for R.sub.5 and R.sub.6 and/or R.sub.7 and R.sub.8 to form an optionally substituted, saturated C.sub.5 -C.sub.12 ring, X represents O or --(CR.sub.9 R.sub.10).sub.n with n=1 or 2 and R.sub.9 and R.sub.10 represent H or CH.sub.3 ; if X represents --(CR.sub.9 R.sub.10).sub.n, R.sub.6 and R.sub.8, with the atoms of the ring to which they are attached, form a bicyclic system having 7 or 8 carbon atoms; if X represents --(CR.sub.9 R.sub.10).sub.n with n=1, R.sub.9 and R.sub.10 =CH.sub.3, R.sub.5 =H and R.sub.6 and R.sub.8, with the atoms of the ring to which are attached, form a bicyclic system having 7 carbon atoms, R.sub.7 can represent a --CH.sub.2 SO.sub.3 H residue, optionally in salt form. Process for preparing these compounds and their use as antioxidants and medicinal products for the treatment of skin allergies and inflammations.

New benzylcyclanone derivatives process for preparing them and cosmetic

The invention relates to cosmetic and pharmaceutical compositions containing the derivatives of benzylidenecamphor of formula: ##STR1## where R.sub.1 denotes H, OH, C.sub.1 -C.sub.3 alkyl or C.sub.1 -C.sub.8 alkoxy, R.sub.3 denotes OH, C.sub.1 -C.sub.3 alkyl or C.sub.1 -C.sub.8 alkoxy, or else when R.sub.1 denotes H or OH, R.sub.3 can represent C.sub.1 -C.sub.8 alkyl, R.sub.2 and R.sub.4 denote H or OH, at least one of the radicals R.sub.2 and R.sub.4 representing OH. The compounds (I) are wide-band sunscreens and antioxidants, and are utilized in the treatment of cutaneous inflammations and allergies.

Cosmetic and pharmaceutical compositions containing lipophilic

A 5,6,7,8-tetrahydro-1-naphthalenol derivative of the formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 represent lower alkyl,

Cosmetic and pharmaceutical compositions containing naphthalenol

New derivatives of 5,6,7,8-tetrahydro-1-naphthalenol, a process for

The invention relates to benzylidenecamphor derivatives of formula: ##STR1## where R is hydrogen or a tert-butyl residue, R.sub.1 is a C.sub.1 -C.sub.8 alkyl or alkoxy residue, and R.sub.2 and R.sub.3 denote hydrogen or hydroxyl, at least one of the two being hydroxyl, to a process for preparing them and to their uses as antioxidants, broad-band sunscreens and medicinal products for the preventive treatment of skin allergies and inflammations as well as for the prevention of certain cancers.

Tert-butyl derivatives of benzylidenecamphor, process for preparing

A composition for treatment and treatment of certain skin diseases is disclosed. The treatment combines furocoumarins, UV-A radiation, and a benzylidene-camphor derivative. The composition and treatment produces the desirable results of the furocoumarin/UV-A radiation treatment without the undesirable phototoxic side effects.

Medicinal combination used in photochemotherapy

The present invention relates to a cosmetic composition comprising a natural essence containing a phototoxic dose of furocoumarin, and 0.01 to 2% by weight of at least one benzylidenecamphor derivative filtering out UV-A radiation and chosen from among 3-p-oxybenzylidenebornan-2-ones, 3,3'-terephthalylidenedicamphors optionally sulfonated in the 10-position of the camphor, p-(3-methylidenecamphor)-cinnamic acid derivatives, 3,3'-terephthalylidenedicampho-10-sulfonamides or 3,3'-terephthalylidenedicampho-10,10'-disulfonamides. It is also possible to incorporate into the composition a UV-B filter chosen from among: benzylidenecamphor, p-methylbenzylidenecamphor, benzylidenecamphor derivatives containing a quaternary ammonium radical on the benzene nucleus in the para position relative to the bornylidene radical, benzylidenecamphor derivatives sulphonated on the methyl radical in the 10-position of the camphor or in the 3'-position of 4'-position on the benzene nucleus, p-methylbenzylidene-camphor derivatives substituted on the p-methyl group, or other 3-benzylidenecamphor derivatives filtering out UV-B radiation. The effect of the benzylidenecamphor derivative is to deactivate the furocoumarins excited by UV radiation and to reduce their phototoxicity.

Growing community of inventors

Orry-la-Ville, France

Andre Deflandre