Vepex Contractor Ltd.

Mta Szegedi Biologiai Kozpontja

Skandigen Ab

Andras Simoncsits

Miklos Kalman

Imre Cserpan

Csaba Kari

Gyorgy Bajszar

Bertil Aberg

A structural gene coding for authentic human serum albumin, --optionally supplemented by an upstream triplet coding for methionine and optionally extended by a synthetic prepro.sup.x -leader-coding sequence--, wherein the codons of the nucleotide sequence have been selected with regard to a non-human host, e.g. yeast, chosen for expression of authentic human serum albumin, is disclosed. Additionally there is disclosed a method of producing said gene. There are also disclosed a recombinant DNA molecule comprising said strucural gene inserted into a vector, and a host transformed with said recombinant DNA molecule. Furthermore there are disclosed a method of producing authentic human serum albumin, an authentic human serum albumin resulting from said method, and a pharmaceutical composition comprising said resulting human serum albumin.

Artificial gene coding for authentic human serum albumin, use thereof

The invention relates to a process for the preparation of oligo- and polydeoxyribonucleotides by synthesizing the complementary strand of a single-stranded DNA piece enzymatically, in the presence of deoxyribonucleoside 5'-triphosphates in a cloning vector.

Process for the preparation of oligo- and polydeoxyribonucleotides

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Szeged, Hungary

Andras Simoncsits