Cis Bio International

Andr&eacute; Roget

Thierry Livache

Robert Teoule

Christelle Barthet

G&eacute;rard Bidan

A method for preparing a copolymer of general formula (I) by electrochemically copolymerising a compound of general formula (II) with a compound &lsqb;A&rsqb;, wherein &lsqb;A&rsqb; is a monomeric unit of a polymer capable of being produced by electrochemical copolymerisation, &lsqb;B&rsqb; is a side group that may be a monomer or a polymer and is bound to unit &lsqb;A&rsqb; by a covalent bond or via a spacer arm, and x and y are integers of a least 1. Said method includes a treatment enabling the surface reactivity of said copolymer to be reduced.

Method for reducing the surface reactivity of copolymers produced by electrochemical polymerization

A copolymer of general formula (I), wherein unit A is a monomer of an electronically conductive polymer, unit B is a nucleotide, an oligonucleotide or an analogue thereof, x, y, z are integers of 1 or higher or y is 0, and 1 is a covalent bond, or a spacer arm. Methods for preparing polymer (I) and its use, in particular for nucleic acid synthesis, sequencing and hybridization, are also disclosed.

Electronically conductive polymer/nucleotide copolymer. preparation method therefor and use thereof

The invention relates to nucleoside derivatives bearing electrolabile protector groupings and their use in an oligonucleotide synthesis method comprising at least one step of electronic deprotection.

Growing community of inventors

Saint Egreve, France

André Roget

Growing community of inventors

Saint Egreve, France

Andr&eacute; Roget

André Roget