The University of British Columbia

Anders Klaus

Carl Lars Genghis Hansen

Jens Huft

Sohrab Shah

Hans Zahn

Samuel Alves Jana Rodrigues Aparicio

Adi Steif

Marinus Theodorus Johannes Van Loenhout

Kaston Leung

Bill Kengli Lin

Sohrab Prakash Shah

Methods, devices and systems for analyzing precious samples of cells, including single cells are provided. The methods, devices, and systems in various embodiments of the invention are used to assess genomic heterogeneity, which has been recognized as a central feature of many cancers and plays a critical role in disease initiation, progression, and response to treatment. The methods devices and systems are also used to analyze embryonic biopsies for preimplantation genetic diagnosis (PGD). In one embodiment, the devices, systems and methods provided herein allow for the construction of genomic and RNA-seq libraries without a pre-amplification step.

Methods for analyzing genomic variation within cells

Growing community of inventors

Vancouver, Canada

Anders Klaus