Nycomed Imaging As

Amersham Health As

Photocure As

Anders H&oslash;gset

Jo Klaveness

Alan Cuthbertson

Magne Solbakken

P&aring;l Rongved

Lars Hoff

Halldis Hellebust

Helge Tolleshaug

Anne N&aelig;vestad

Dagfinn L&oslash;vhaug

Klaus Bryn

Aslak Godal

Johan E Moan

Kristian Berg

Geir Gogstad

Kirsten Sandvik

Targetable diagnostic and/or therapeutically active agents, e.g. ultrasound contrast agents, comprising a suspension in an aqueous carrier liquid of a reporter comprising gas-containing or gas-generating material, said agent being capable of forming at least two types of binding pairs with a target.

Diagnostic/therapeutic agents

The present invention relates to a method for introducing molecules in cells by disrupting endosomal and lysosomal membranes using photodynamic treatment, without killing the majority of the cells by the photodynamic treatment. More particularly, this invention includes a method for transferring DNA and/or RNA, such as genes, to cells by photochemically inducing the disruption of endosomes and lysosomes.

Transfer of molecules into the cytosol of cells

Targeted diagnostic/therapeutic agents having more than one different vectors

Targetable diagnostic and/or therapeutically active agents, e.g. ultrasound contrast agents, having reporters comprising gas-filled microbubbles stabilised by monolayers of film-forming surfactants, the reporter being coupled or linked to at least one vector.

Diagnostic/therapeutic agents having microbubbles coupled to one or more vectors

Growing community of inventors

Oslo, Norway

Anders Høgset

Growing community of inventors

Oslo, Norway

Anders H&oslash;gset

Anders Høgset