Abbvie Inc.

Anca Clabbers

Chung-Ming Hsieh

Jennifer Maria Perez

Yuliya Kutskova

John Memmott

Suju Zhong

Margaret Hugunin

Edit Tarcsa

Mary Leddy

Anwar Murtaza

Bradford L McRae

Craig Wallace

Shaughn H Bryant

Lorenzo Benatuil

Lucia Eaton

Tariq Ghayur

Ravi Chari

Jijie Gu

Feng Dong

Carrie Goodreau

Alyssa Brito

Diana Bowley

Matthew Rieser

Binding proteins that bind one or more of VEGF, PDGF and/or their receptors, including antibodies, CDR-grafted antibodies, humanized antibodies, binding fragments, fusion proteins, and bispecific or multispecific proteins thereof are disclosed. Also disclosed are methods of making and using the binding proteins.

Antibodies against platelet-derived growth factor (PDGF)

Isolated binding proteins, e.g., antibodies or antigen binding portions thereof, which bind to tumor necrosis factor-alpha (TNF-&#x3b1;), e.g., human TNF-&#x3b1;, and related antibody-based compositions and molecules are disclosed. Also disclosed are pharmaceutical compositions comprising the antibodies, as well as therapeutic and diagnostic methods for using the antibodies.

Immunobinders directed against TNF

Proteins that bind IL-17 and/or IL-17F are described along with their use in composition and methods for treating, preventing, and diagnosing IL-17 related diseases and for detecting IL-17 in cells, tissues, samples, and compositions.

IL-17 binding proteins

Engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease are provided.

Bispecific antibodies directed against TNF-&#x3b1; and IL-17

Proteins that bind IL-17 and/or IL-17F are described along with their use in compositions and methods for treating, preventing, and diagnosing IL-17 related diseases and for detecting IL-17 in cells, tissues, samples, and compositions.

Proteins that bind IL-17 and/or IL-17F are described along with there use in composition and methods for treating, preventing, and diagnosing IL-17 related diseases and for detecting IL-17 in cells, tissues, samples, and compositions.

Growing community of inventors

Rutland, MA, United States of America

Anca Clabbers