Prosetta Antiviral, Inc.

Prosetta Biosciences, Inc.

Anatoliy Kitaygorodskyy

Andy Atuegbu

Clarence R Hurt

Vishwanath R Lingappa

Dennis Solas

Beverly Freeman

Kumarapandian Paulvannan

Described herein are compounds, pharmaceutical compositions and methods of using these compounds and pharmaceutical compositions for treating and/or preventing conditions such as amyotrophic lateral sclerosis. These compounds and pharmaceutical compositions are also useful as antivirals and antimicrobial agents.

Isoquinoline derivatives, methods of synthesis and uses thereof

This invention provides, among other things, tetrahydroisoquinolines useful for treating viral infections, pharmaceutical formulations containing such compounds, as well as methods of inhibiting the replication of a virus, such as HIV, or treating a disease, such as AIDS.

2-phenethenyltetrahydro isoquinolines useful as anti-HIV compounds

Anti-HIV compounds

Compounds and methods for preventing and treating viral infections are provided. In some embodiments, novel compounds broad-spectrum antiviral activity are provided. In more specific embodiments, the compounds and methods are effective against viruses such as Venezuelan Equine Encephalitis, West Nile Virus, and Hepatitis C.

Antiviral compounds

Compounds and methods for preventing and treating viral infections are provided. In some embodiments, novel compounds broad-spectrum antiviral activity are provided. In more specific embodiments, the compounds and methods are effective against viruses such as Venezuelan Equine Encephalitis, West Nile Virus, and respiratory viruses including the common cold.

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San Francisco, CA, United States of America

Anatoliy Kitaygorodskyy