Other

Presbyopia Treatments Limited

Eye Comfort Limited

Optosolve Research & Development Limited

Sharma, Anant

Photon Therapeutics Limited

Anant Sharma

Jonathan Moore

Laurent Le Mentec

Benjamin Sharma

Benjamin Anand Ruben Sharma

Laurent Lementec

Ginny Conde

Leon Williams

Belén Iglesias Bares

The present disclosure describes compositions which improve visual acuity and to methods for their use.

Optical correction

Aqueous compositions suitable for topical administration to the human or animal eye contain at least one water-soluble polymeric ophthalmic lubricant, such as hyaluronate, carbomer gel or hypromellose, together with a water-soluble analgesic. The analgesic may be an opiod, particularly an opioid having an affinity for 5-HT receptors, such as tramadol. The aqueous compositions may for example be used as artificial tears, and as general ophthalmic lubricants for treating conditions such as dry eye or blepharitis. Further compositions combine ophthalmologicallyactive agents, such as pharmaceuticals, with opioids, such as tramadol in particular. These compositions may be used to treat the eye while reducing pain or discomfort that would normally be produced by administering these particular pharmaceuticals to the eye, and increasing the efficacy of the pharmaceuticals. Compositions are also disclosed, containing opioids with 5-HT receptor activity, which are of general use in alleviating pain in and around the eye.

Opthalmic treatments

A manual device for massaging one or both of the upper and lower lids of the eye, the device including: a body, composed of flexible resilient biocompatible material, wherein the body provides jaws or lips, wherein the lips are biased into a spaced relationship by the material of the body, and wherein each lip is adapted to engage either the upper or lower eyelid, such that movement of the lips causes movement of at least one eyelid with respect to the other. The devices can conveniently be used to manipulate the meibomian glands of the eye in an optimum orientation, for example for alleviating or treating dry eye.

Eye massage device

Infections of body tissues, particularly of the eye or of wounds, are treated by brief low-intensity irradiation with ultraviolet radiation in the UVC band. A suitable treatment device contains a light-emitting diode producing UVC radiation at a wavelength of about 265 nm, at a power output of 5 mW, directed on to a zone of tissue about 4 mm in diameter. An optical aiming system indicates the zone of tissue to be irradiated. Irradiation for periods as brief as 1 second has been found effective, which equates to a dose of 4 mJ/cmdelivered to the tissue. Longer periods and higher intensities may be used for more resistant infections. Such irradiation may be delivered endoscopically to treat internal infections or to prevent infection during surgery. The device may be hand held or mounted to an ophthalmic slit lamp or other support.

Method of treating an eye infection using electromagnetic radiation in the UVC

Massage appliance

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Bedford, United Kingdom

Anant Sharma