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Katholieke Universiteit Leuven, Ku Leuven R&d

Ucb Pharma, S.a.

Ucb Biopharma Sprl

Ucbbiopharma Srl

Anant Ramrao Ghawalkar

James Thomas Reuberson

Daniel James Ford

Richard Jeremy Franklin

Daniel Christopher Brookings

Bart Vanderhoydonck

Qiuya Huang

Claire Louise Kulisa

Judi Charlotte Neuss

Helen Tracey Horsley

Jean Herman

Thierry Louat

A series of pyrazolo[3,4-d]pyrimidine derivatives that are substituted at the 4-position by a diaza monocyclic, bridged bicyclic or spirocyclic moiety, are beneficial in the treatment and/or prevention of various human ailments, including inflammatory, autoimmune and oncological disorders; viral diseases and malaria; and organ and cell transplant rejection.

Therapeutically active pyrazolo-pyrimidine derivatives

Compounds of formula (I) i.e. monocyclic or bicyclic diamine-substituted thieno[2,3-d]pyrimidine and isothiazolo[5,4-d]pyrimidine derivatives substituted by an optionally substituted oxazolin-2-yl moiety, are beneficial in the treatment and/or prevention of various human ailments, including inflammatory, autoimmune and oncological disorders; viral diseases; and organ and cell transplant rejection. 

Therapeutically active oxazoline derivatives

A series of monocyclic or bicyclic diamine-substituted thieno[2,3-d]pyrimidine and isothiazolo[5,4-d]pyrimidine derivatives are beneficial in the treatment and/or prevention of various human ailments, including inflammatory, autoimmune and oncological disorders; viral diseases; and organ and cell transplant rejection.

Therapeutically active fused pyrimidine derivatives

A series of thiazolo[5,4-d]pyrimidine derivatives of formula (I) or an N-oxide thereof, or a pharmaceutically acceptable salt or solvate thereof: (I) Q represents a group of formula (Qa), (Qb), (Qc), (Qd) or (Qe) are beneficial in the treatment and/or prevention of various human ailments, including inflammatory, autoimmune and oncological disorders; viral diseases; and organ and cell transplant rejection. 

Therapeutically active thiazolo-pyrimidine derivatives

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Hyderabad Telangana, India

Anant Ramrao Ghawalkar