Aurobindo Pharma Limited

Avrobindo Pharma Ltd.

Anand Gopalkrishna Kamat

Sivakumaran Meenakshisunderam

Naga Trinadhachari Ganala

Joseph Prabahar Koilpillai

Venkata Balaji Boddu

Sivakumaran Meenaakshisunderam

Venkata Lakshmi Upputuri

Narsimha Reddy Penthala

Venkata Balalji Boddu

Ganala Naga Trinadhachari

Boddu Venkata Balaji

The present invention relates to novel solvates of Darunavir of Formula I. 

Solvates of darunavir

The present invention relates to a process for the preparation of Solifenacin succinate by condensing a compound of formula (IVb) with (RS)-3-quinuclidinol, wherein, R represents methyl, ethyl, isopropyl; to produce a diastereomeric mixture of (1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic acid (3RS)-1-azabicyclo[2.2.2]oct-3-yl ester, which is treated with succinic acid in a solvent or mixture of solvents to produce optically pure Solifenacin succinate, Formula (X). 

Process for the preparation of solifenacin succinate

The invention relates to an process for preparing Tamsulosin hydrochloride of Formula (I) which comprises (i) reacting (R)-(&#x2212;)-5-(2-amino-propyl)-2-methoxybenzenesulfonamide of Formula (II) with substituted phenoxy compound of Formula (III), wherein Z represents a removing group, such as &#x2014;OSOCH, &#x2014;OSOCHCH, &#x2014;F, &#x2014;Br, &#x2014;Cl, or &#x2014;I, in a solvent in the presence of an alkaline earth metal oxide to obtain Tamsulosin base and (ii) converting Tamsulosin base into hydrochloride salt in a solvent by addition of aqueous hydrochloric acid. 

Process for preparing tamsulosin hydrochloride

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Hyderabad Telangana, India

Anand Gopalkrishna Kamat