Association for the Advancement of Tissue Engineering and Cell Based Technologies & Therapies (a4tec) - Associacão

Universidade Do Minho

Association for the Advancement of Tissue Engineer

Universidade Nova De Lisboa

Association for the Advancement of Tissue Engineering Cell Based Technologies & Therapies (a4tec) - Associação

Nova.id.fct - Associação Para a Inovação E Desenvolvimento Da Fct

Ana Rita Cruz Duarte

Rui Luis Gonçalves Dos Reis

Jorge Manuel Nunes Correia Pinto

Alexandre António Antunes Barros

Estêvão Augusto Rodrigues De Lima

Carlos André Ribeiro Oliveira

Ana Alexandra Figueiredo Matias

Rui L Reis

Rui Miguel Fernandes Duarte

Carolina Velhinho Pereira

Alexandre Babo De Almeida Paiva

Rui Luis GONÇALVES Reis

Rui Luis GONÇALVES Dos Reis

Tiago José Quinteiros Lopes Henriques Da Silva

João Carlos Fernandes Da Silva

Ivo Manuel De ASCENSÃO Aroso

The present disclosure relates to biodegradable ureteral stents comprising an anti-cancer drug, and to a composition for use in medicine that may be used to ensure patency of a channel, namely a mammal ureter, for example, an obstructed ureter by a urinary stone, neoplasia or by a surgical procedure. The biodegradable ureteral stents (BUS) disclosed in the present disclosure unexpectedly allow a proper release of anti-cancer drugs, thus extending the duration of the treatment and increasing the efficacy of the treatment.

Biodegradable ureteral stents, methods and uses thereof

The present disclosure relates to injectable and expandable compositions, devices, kits and methods for use in an approach for the in-situ foaming of polymers for bone or tissue defects, namely to fill and/or fuse a tissue defect. The present disclosure relates to compositions, devices, kits and methods for use in an approach for the in-situ foaming of polymers for bone or tissue defects, namely for bone tissue defect filling/fusion. The design of extendable and expandable compositions for bone fusion is one of the most challenging fields in the intersection of polymer and biomedical engineering. An aspect of the present disclosure relates to an injectable expandable composition for use in medicine, veterinary or cosmetic, comprising a polycaprolactone particle filler; a polydopamine adhesive bound to said filler; a polymethacrylic acid plasticizer bound to said polydopamine adhesive.

Injectable and expandable composition, devices, kits, methods and uses thereof

Stents and methods for producing stents are provided. The stent includes a polymeric substrate comprised of 10-50% (w/w) of alginate and 45-85% (w/w) of gelatine and further includes a polymeric biodegradable resin for coating said polymeric substrate. The stent can also include a contrast agent. The stent can further include a crosslinking agent. The method for producing the stent includes dissolving the alginate and gelatine in water and stirring to obtain a polymeric substrate. The method also includes adding a crosslinking agent to the substrate, injecting the substrate into a mold to obtain the stent, placing the stent in a first alcohol solution, and placing the stent in a crosslinking agent solution. The method further includes placing the stent in a second alcohol solution, and a series of interchanging drying and immersing steps.

Ureteral stent, methods and uses thereof

Growing community of inventors

Braga, Portugal

Ana Rita Cruz Duarte