Miroculus Inc.

Ana Eugenia Carvajal

Mais Jehan Jebrail

Foteini Christodoulou

Eduardo Cervantes

Rohit Lal

Mark Lewis

Spencer Seiler

Nikolay Sergeev

Mathieu Gabriel-Emmanuel Chauleau

Poornasree Kumar

Alejandro Tocigl Domeyko

Air-matrix digital microfluidics (DMF) apparatuses and methods of using them. These methods and apparatuses may include the use of a liquid wax coating material and/or pinning the encapsulated reaction droplet within the air gap using pinning features. Any of these methods may also include separating the liquid wax from an encapsulated aqueous droplet, e.g., using an oil absorbent wick to selectively separate the liquid oil or wax from the aqueous droplet by adsorbing and/or absorbing the liquid wax into the absorbent wick while leaving the aqueous droplet behind.

Control of evaporation in digital microfluidics

Methods and apparatuses for sequencing by synthesis using mechanical compression. These methods and apparatuses may mechanically control microfluidic movement using a force applicator and an elastically deformable sheet.

Sequencing by synthesis using mechanical compression

Methods and apparatuses for mechanically controlling microfluidic movement using a force applicator and an elastically deformable sheet are described herein. These apparatuses may include a mechanical microfluidics actuator devices and a cartridge. A microfluidic droplet may be moved or displaced within an air gap of the cartridge by applying a compressive force locally and selectively reduce the gap width of the air gap near the microfluidic droplet causing the microfluidic droplet to move toward the reduced gap. Compressive forces may also be used to divide, join, mix or perform other operations on the microfluidic droplets.

Methods of mechanical microfluidic manipulation

Growing community of inventors

San Francisco, CA, United States of America

Ana Eugenia Carvajal