Unitech Pharmaceuticals, Inc.

Other

National Defense Medical Center

Geneblue Corporation

Giant Force Technology Corporation

An-Rong Lee

Wen-Hsin Huang

Jiajiu Shaw

Wen-Liang Chang

Chen-Wen Yao

Chi-Hong Chu

Ann Chen

Kuo-Yuan Hwa

Li-Heng Pao

Chiao-Ying Chien

Chien-Yi Pai

The present invention relates to a use of mycophenolate mofetil or a pharmaceutically acceptable salt thereof in the manufacture of a medicament against influenza virus. The present invention also relates to a use of mycophenolate mofetil or a pharmaceutically acceptable salt thereof in the manufacture of a medicament against drug-resistant influenza virus strains. The present invention is further related to a method for treating influenza in a subject, comprising administering to said subject an effective amount of mycophenolate mofetil or a pharmaceutically acceptable salt thereof.

Usage of mycophenolate mofetil or salt thereof in preparing drug for resisting against influenza virus

Disclosed are an Schisandrae fructus extract for inhibition or prevention of influenza and its application, wherein the Schisandrae fructus extract is obtained by water, methanol, or ethanol extraction process and the extract comprises compounds such as schisandrone, benzoylgomisin P, wulignan A1, epigomisin O, epiwulignan A1, and tigloylgomisin P. The extracts and purified compounds of Schisandrae fructus has anti-influenza virus H1N1 and H1N1-TR (a Tamiflu drug resistant virus strain) activities, therefore the extracts and the purified compounds of Schisandrae fructus can be applied as an inhitibory agent of a pharmaceutical composition for treatment or prevention agent for influenza infection.

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A series of isoxazole derivatives and methods of suppressing, inhibiting, or preventing disorders mediated by nitric oxide (NO) and/or proinflammatory cytokines, such as TNF-&#x3b1; (tumor necrosis factor alpha), IL-1 (interlukin-1), and IL-6, are described.

Isoxazole derivatives and methods of treating nitric oxide mediated diseases

Methods of treating cancer employing isoxazole derivatives are described. Compounds and methods of using these compounds for isolating and/or detecting binding proteins, which may be indicative of a disease, are also described.

Methods, compounds, and diagnostics for cancer treatment

Novel leflunomide analogs were synthesized and evaluated in-vivo. Based on the in-vivo studies, these analogs are surprisingly effective for treating rheumatoid arthritis.

Leflunomide analogs for treating rheumatoid arthritis

In the invention of novel nonsteroidal antiinflammatory compounds the title novel triazole compounds, were synthesized from carboxylic acids, 2,5-acetonylacetone, or isoniazid, respectively. To give 4H-1,2,4-triazol-3-thiols. Treatment of 4H-1,2,4-tri-azol-3-thiols with methyl chloroacetate or methyl .alpha.-chloropropionate resulted in the formation of compounds I-VI. The antiinflammatory activity of those new triazole compounds were determined by the carrageenin-induced edema method and they showed potent activity. In the dosage form studies those compounds of formula I-VI were added suituble vehicleo to prepare antiinflammatory agents.

Growing community of inventors

Taipei, Taiwan

An-Rong Lee