The Procter Gamble Company

Alimentary Health Limited

Amy Violet Trejo

Juan Esteban Velasquez

Gregory Allen Penner

Kelly Lee Schmeichel

Erin Swigart

Adam Michael Pitz

Spencer Christopher Rupard

Paul Albert Sagel

Liam Diarmuid O'Mahony

Stevan David Jones

Douglas Joseph Dobrozsi

Laurie Ellen Breyfogle

James Patrick Henry

Liam Diamuid O'Mahony

An aptamer composition is disclosed which has one or more oligonucleotides that include at least one of deoxyribonucleotides, ribonucleotides, derivatives of deoxyribonucleotides, derivatives of ribonucleotides, or mixtures thereof. The aptamer composition has a binding affinity for one or more cellular membrane glycoproteins selected from the group consisting of: intercellular adhesion molecule 1 (ICAM-1), low-density lipoprotein receptor (LDLR) family members, and cadherin-related family member 3 (CDHR3), preferably intercellular adhesion molecule 1 (ICAM-1), and is configured to reduce the binding of one or more human rhinoviruses to the intercellular adhesion molecule 1 (ICAM-1).

Aptamers for personal health care applications

Nucleic acid aptamers having a high binding affinity and specificity for malodorous molecules and the use of such aptamers to reduce the intensity of the undesirable smells in personal care compositions.

Aptamers for odor control applications

The present invention is directed to an aptamer composition comprising at least one oligonucleotide consisting of: deoxyribonucleotides, ribonucleotides, derivatives of deoxyribonucleotides, derivatives of ribonucleotides, and mixtures thereof; wherein said aptamer composition has a binding affinity for one or more fungi species from the genus

Aptamers for personal care applications

Consumer product compositions comprise a surfactant and a nucleic acid aptamer. The nucleic acid aptamer comprises at least one oligonucleotide comprising: deoxyribonucleotides, ribonucleotides, derivatives of deoxyribonucleotides, derivatives of ribonucleotides, or mixtures thereof. The nucleic acid aptamer has a binding affinity for an epitope of a surface being treated with the consumer product composition.

Aptamers for consumer product compositions

Methods of use in humans of probiotic bacteria of the genusfor regulating the condition of human keratinous tissue to achieve cosmetic beauty benefits. Said methods include regulation, either prophylactic or therapeutic, of the cosmetic appearance of human keratinous tissue, such as human hair, skin (e.g., scalp), and nails. In another aspect, the invention provides a method of marketing a composition comprising probiotic. In one embodiment, the method comprises: (1) offering for sale a composition comprising probiotic; and (2) communicating to a potential consumer of said composition that oral administration of said composition can regulate the condition of human keratinous tissue.

Methods of use of probiotic bifidobacteria for human beauty benefits

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Oregonia, OH, United States of America

Amy Violet Trejo