Massachusetts Institute of Technology

Dana-Farber-Cancer Institute Inc.

Dartmouth College

Amy E Keating

Justin Michael Jenson

Loren D Walensky

Gregory H Bird

Jianfu Zhou

Vincent Xue

Gevorg Grigoryan

Raheleh Rezaei-Araghi

Provided herein are peptides selective for combinations of Mcl-1/Bfl-/Bcl-xL. Also provided are compositions containing these polypeptides and methods of using such peptides in the treatment of cancer that include administering to a subject one of the polypeptides.

Peptides selective for Bcl-2 family proteins

Provided herein are compounds comprising peptides that bind Bfl-1. Also provided are compositions containing these peptides and methods of using such peptides in the treatment of cancer that include administering to a subject one of the peptides.

Selective Bfl-1 peptides

Provided herein are stabilized peptides that bind Mcl-1. Also provided are compositions containing these polypeptides and methods of using such peptides in the treatment of cancer that include administering to a subject one of the polypeptides.

Selective Mcl-1 binding peptides

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Arlington, MA, United States of America

Amy E Keating