Second Sight Medical Products, Inc.

Amy Chu Peishuan Hines

Robert Jay Greenberg

Dao Min Zhou

Mark Salman Humayun

James David Weiland

Samip Shah

Arup Roy

Rongqing Dai

The present invention is a method for measuring stable and reproducible electrode-tissue impedance, comprising preconditioning an electrode-tissue interface. Further aspect of the invention is a stimulation system for a visual prosthesis generating a stimulation signal to precondition the electrode-tissue interface, comprising a computer; software, loaded in the computer, adapted to perform a stimulating method for a visual prosthesis having a plurality of electrodes; a video processing unit; and an implanted neuron-stimulator.

Method for measuring stable and reproducible electrode-tissue impedance

A critical element of a retinal prosthesis is the stimulating electrode array, which is placed in close proximity to the retina. It is via this interface that a retinal prosthesis electrically stimulates nerve cells to produce the perception of light. The impedance load seen by the current driver consists of the tissue resistance and the complex electrode impedance. The results show that the tissue resistance of the retina is significantly greater than that of the vitreous humor in the eye. Circuit models of the electrode-retina interface are used to parameterize the different contributors to the overall impedance.

Method of improving electrode tissue interface

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Monterey Park, CA, United States of America

Amy Chu Peishuan Hines