Life Technologies Corporation

Amy Castillo

Cheng-Yao Chen

Daniel Mazur

Stephen P Hendricks

Marian Peris

Michael Phelan

Xinzhan Peng

Disclosed herein are modified polymerase compositions exhibiting altered polymerase activity, which can be useful in a variety of biological applications. Also disclosed herein are methods of making and using such compositions. In some embodiments, the compositions exhibit altered properties that can enhance their utility in a variety of biological applications. Such altered properties, can include, for example, altered nucleotide binding affinities, altered nucleotide incorporation kinetics, altered photostability and/or altered nanoparticle tolerance, as well as a range of other properties as disclosed herein.

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Houston, TX, United States of America

Amy Castillo