Wisconsin Alumni Research Foundation

Amy C Wong

Ferencz S Denes

Eileen B Somers

Douglas J Beecher

Agnes Reka Denes

Passivation of bacterial biofilm exposed surfaces is carried out utilizing cold-plasma treatments. Exposure of a substrate with biological contamination thereon to an oxygen plasma sterilizes and cross-links the biological contamination into a form which is resistant to further adhesion of bacteria and other biomaterials while cleansing and sterilizing areas of the substrate that are not covered by the biofilm. A second step may be carried out to plasma mediate the deposit of an anti-fouling film using components that will provide macromolecular networks on the substrate with a desired structure which is resistant to bacterial adhesion.

Plasma-aided treatment of surfaces against bacterial attachment and

The characterization of the protein structure of an enterotoxin to Bacillus cereus, designated hemolysin BL, is described herein. A high-yield purification scheme which allows quantitative characterization of the hemolysin BL activity is also described.

Growing community of inventors

Madison, WI, United States of America

Amy C Wong