Other

Amy C Little

James E Swon

Pradeepkumar P Sanghvi

Henry Z Hofer

Charles C Collins

In a transdermal cell, a matter volume-adjustment male device includes the lower opening end of the through-space structure having inner wall female threads mateable with first male threads of a screwable matter volume-adjustment male member alternately adjustable upwardly and downwardly between opposite upper and lower female threads-termination points. The screwable matter volume-adjustment member has opposite first upper and lower male threads-termination points, and the inner wall female threads are further concurrently mateable with a bottom closure member having second male threads having opposite second upper and lower male threads-termination points. There is a first annular sealing ring sealably mounted in an annular groove around the screwable volume-adjustment male member between the first upper and lower threads-termination points positioned between the inner wall female threads and the first male threads, and there being a second annular sealing ring sealably mounted the second male threads at a location below the second upper termination point.

Transdermal cell test matter volume-adjustment device

In a preferred embodiment of the invention, a transdermal patch holder is provided for making possible an ascertaining of drug release rate of a transdermal patch mountable thereon. The holder includes upper and lower spaced-apart aligned annular adapter disc structures forming aligned through-spaces. An upper surface of the lower disc structure has a centrally positioned stepped indentation forming a recess space seatable of the transdermal patch. The lower surface of the upper disc structure has a centrally positioned stepped downwardly-extending projection of slightly lesser cross-section than the cross-section of the recess space and is adapted to downwardly press upon an upper surface of a seated transdermal patch when the upper disc structure is intermittently in a latched state of being latched to the lower disc structure. A latching mechanism provided by outer circumscribing upright edges at each of opposite sides of each of the upper and lower disc structures has spaced-apart cut-aways forming a radially outwardly extending lateral projection therebetween, and lateral projections of the upper and lower disc structures aligned and having elastic annular bands intermittently mounted thereon securable of the upper and lower disc structures in face to face relationship. A transdermal patch is mountable and may be thereby held therebetween, with a handle-tab of the patch being seatable in and extendable through a laterally extending channel to laterally exterior space.

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Atlanta, GA, United States of America

Amy C Little