Richter Gedeon Nyrt.

Amrita Agnes Bobok

Monika Vastag

Istvan Gyertyan

Katalin Saghy

Janos Galambos

Katalin Nogradi

Ottilia Elekes

Krisztina Gal

Csaba Weber

Ibolya Prauda

Gabor Wagner

Krisztina Gál

Gabor Andras Wagner

Provided herein are Thieno[2,3-b]pyridine compounds with mGluR activity. Also provided herein are processes and intermediates for the preparation of the Thieno[2,3-b]pyridine compounds, pharmaceutical compositions containing these compounds, and the use of these compounds in treatment, therapy, and/or prevention of conditions which require modulation of mGluR1 and mGluR5 receptors.

Thieno [2,3-b] pyridine compounds with mGluR activity

The present invention relates to new mGluR1 and mGluR5 receptor subtype preferring ligands of formula (I) and/or salts and/or hydrates and/or solvates and/or polymorphs thereof. The invention also relates to processes and intermediates for their preparation, to pharmaceutical compositions containing these compounds and to their use in treatment and/or prevention of conditions which require modulation of mGluR1 and mGluR5 receptors.

Sulfonyl-quinoline derivatives

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Budapest, Hungary

Amrita Agnes Bobok