Random Technologies LLC

Keimar Corporation

Foxs Labs

Amos Gottlieb

William Kilbridge

Paul Douglas Corl

Henry K Hui

Harry D Nguyen

Margaret R Webber

David L Crain

George Allen

Apparatus, and components for use in apparatus, for changing the concentration of a selected gas in a liquid, for example for degassing liquids. In one apparatus, the apparatus has a flow channel (a) through which the liquid is passed, and (b) which comprises a wall comprising a planar separation membrane, and (c) has a height of 0.00025-0.01 and an aspect ratio (width to height) of at least 25:1. One component, which can be used to support a separation membrane, comprises (a) an inner selection plate surface which comprises (i) a selection plate base and (ii) selection plate elements which (a) extend from the base, (b) are separated by intercommunicating selection areas, and (c) have outer surfaces remote from the selection plate base. Another component is a planar separation membrane which comprises (a) a membrane transmission section, and (b) a membrane peripheral member which surrounds the membrane transmission section and which includes location features which facilitate the location of the membrane at a desired position relative to another component.

Apparatus and methods for changing the concentration of gases in liquids

A planar degasser comprises (1) a flow plate comprising a flow channel, (2) a planar separation membrane comprising a membrane transmission section which has a first major surface and a second major surface, the flow channel being at least in part bounded by the first major surface of the membrane transmission section, (3) a supporting member which supports the second major surface of the membrane transmission section when the pressure on the first major surface is greater than the pressure on the second major surface, and (4) structural features which enable liquid to flow through the flow channel when the pressure on the first major surface is equal to or less than the pressure on the second major surface, for example when there is no longer a vacuum on the second major surface of the membrane transmission section. The structural features can for example be an open channel in the base of the flow plate, or upstanding features on the base of the flow plate, or a passageway which is closed when the vacuum is on, but open when the vacuum is off, for example a passageway having a valve which is controlled by the vacuum.

Apparatus and method for degassing liquids

Apparatus for changing the concentration of a selected gas in a liquid, the apparatus comprising a flow chamber through which the liquid is passed and which comprises a wall comprising a planar separation membrane, the separation membrane being substantially impermeable to the liquid and permeable to the selected gas, characterized in that the separation member extends beyond the flow chamber and provides a seal between components of the apparatus. The apparatus is particularly useful for degassing liquids, for example HPLC eluents and analysis samples.

An apparatus for use with a patient having a vessel carrying blood to ascertain characteristics of the blood. The apparatus includes a display module and a probe having a distal extremity adapted to be inserted into the vessel of the patient and having a proximal extremity coupled to the display module. The probe includes a sensor in the distal extremity for providing an electrical signal to the display module when the probe is disposed in the blood. The probe can have an antithrombogenic surface treatment for inhibiting the adhesion of blood components to the probe when disposed in the blood.

Apparatus for ascertaining blood characteristics and probe for use therewith

The analyte sensing system utilizes a sensor indicator which may be a perlyene derivative, coronene, or naphtho [8,1,2-abc] coronene in an analyte permeable silicone matrix. The matrix is irradiated with light of a specific wavelength, and fluorescence emissions of the dye indicator is measured over two different emission spectra having different sensitivities to the analyte. The emission spectrum which is less sensitive to quenching by the analyte can be used as a reference for determining the analyte concentration based upon a ratio of the intensities of the different emission spectra.

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San Francisco, CA, United States of America

Amos Gottlieb