Council of Scientific and Industrial Research

Kulkarni, Amol, Arvind

Joshi, Rohini, Ramesh

Joshi, Ramesh, Anna

Amol Arvind Kulkarni

Vivek Vinayak Ranade

Dumbala Srinivasa Reddy

Vinay Manoharrao Bhandari

Mrityunjay Keshavprasad Sharma

Ramesh Anna Joshi

Rohini Ramesh Joshi

Bhaskar Datttraya Kulkarni

Vasudevan Natarajan

Paresh Ramesh Athawale

Lakhsmi Vara Prasad Bhagavatula

Venkata Ravi Kumar Darbha

Nayana Tushar Nivangune

Jaydeep Bipin Deshpande

Ranjit Shabu Atapalkar

Prachi Kate

Suneha Patil

Manisha Abdhiman Jagtap

Prachi Ashok Kate

A continuous flow reactor without any moving parts to facilitate solid-liquid reaction without clogging is disclosed herein. It comprises plurality of identical cavities in series/sequence, each cavity being provided with: a pair of inlets at the top to allow entry of reactants into the reactor; an outlet at the bottom to allow the reactants to the next cavity for mixing; and a jacket covering around the cavities to provide heating or cooling effect as per the requirement. The outlet of the previous cavity is inclined at a suitable angle relative to the outlet of the next cavity to prevent clogging and facilitate efficient mixing of the reactants.

Continuous flow reactor

A continuous flow process for the synthesis of metal nanowires using a bubble column reactor. Also disclosed are different types of multiphase bubble column reactors for synthesizing metal nanowires in high yields and purity through a continuous process. The continuous process provides tunability for the aspect ratio of the nanowires.

Continuous flow process for the synthesis of metal nanowires using bubble column reactor

The present invention discloses a process for the oxidation of fatty acids comprises reacting fatty acid with Ocontaining Ofor a period of 0.1-60 min at a temp in the range of −78 to 30 deg C. to obtain the corresponding products, wherein the conversion of the fatty acid is in the range of 80% to 100% and the process is catalyst free and co-oxidant free.

Process for the oxidation of fatty acids

The present invention disclosed a continuous flow and batch process for the separation of metal or metal oxide nanoparticles continuously in a periodic manner at the liquid-liquid interface using a centrifugal separator cum extractor, wherein the nanoparticles are collected at the liquid-liquid interface of the polar and non-polar liquids.

Process for interfacial separation of metal nanoparticles or nanowires using centrifugal separators

The present disclosed an improved process for the synthesis of ivacaftor starting from indole acetic acid ester which can be performed in batch as well as continuous flow synthesis. The present invention further disclosed to a continuous process for the synthesis of compound of formula (II) or formula (III) from compound of formula (I) in continuous flow reactor.

Process for the synthesis of ivacaftor

A multimodal micromixer obstacle for intensification of mixing and performing the reaction in a continuous manner is disclosed herein. The micromixercomprises of plurality of inlets, an outlet and a plurality of channels. The end channels&#x2014;of the channels, have plurality&#x2014;of converging sections having width, to depth ratio ranging 1:1 to 20:1. The intermediate channels have at least, one obstacle having non-circular shape. Each converging section is incomplete ellipse, prolate or oblate shaped having, angle of curvature in the range of 90 to 270&#xb0;. Axes of the inlets are coplanar and perpendicular to the channels. All the components of the micromixer are coplanar.

Continuous micro mixer

A Continuous flow synthesis of nanocrystalline metal oxides by rapid sol-gel process is disclosed. The process disclosed uses an impinging microjet micromixer device to obtain the nano crystalline metal oxides. A method of fabricating and assembling the impinging microjet micromixer is also disclosed herewith.

Sol-gel process for synthesis of nanocrystalline oxides

The invention discloses a glass lined metal micro-reactor with enhanced heat transfer efficiency in continuous flow operation. More particularly, the invention discloses a glass lined micro-reactor that can be reassembled. The invention provides a novel glass lined metal micro-reactor with micro fluidic channels that provide a better mixing, better heat exchange, and better temperature control. The micro fluidic channels machined in the glass lined metal reactor/mixer may be straight, curved, lamellar, flower shaped, or spiral such that the cross sectional area of the micro fluidic channel is configured to suit the cross sectional area of the micro-reactor.

Glass lined metal micro-reactor

A tube in tube continuous glass lined metal reactor includes: concentric tubular segments; (a) outer glass lined tube and (b) an inner glass lined segment disposed in the outer glass lined tube, defining thereby an intermediate glass lined region between the inner segment and the outer tube.

Tube in tube continuous glass-lined reactor

A device which can be used as a flow reactor for synthesis and for discerning the reaction kinetics as well as a flow calorimeter is a need in the art. To fulfill this need, the invention discloses a simple calorimeter that functions as a device to measure reaction kinetics, preferably heat of reaction in a continuous manner, in adiabatic as well as in isothermal conditions. The distinct advantages of the device include online determination of thermokinetic properties, continuous determination of thermokinetic properties and applicable for determination in adiabatic as well as isothermal modes. The device may function independently or may be used in combination with reactors, micro reactors or tubular reactors.

Device for thermokinetic property measurement

A method for treating effluent provides the effluent as an input to an apparatus having a vortex diode with aeration. The apparatus induces a cavitation assisted with aeration for the high rates of ammoniacal nitrogen in an orifice and the vortex diode with or without inserts/stabilizers to generate radicals, which reduce ammoniacal nitrogen of wastewater effectively during effluent treatments.

Apparatus and method for reduction in ammoniacal nitrogen from waste waters

The present invention discloses a flow reactor composed of plurality of modular/fluidic components that helps retain agility and re-configurability of the continuous chemical processes with improved processing ability. More specifically, disclosed herein is a continuous flow reactor composed of varied permutations and combinations of a plurality of modular/fluidic components for chemical processing. The components are connected to each other using connectors that facilitate the connection of either with two or more, similar or different components.

Continuous modular reactor

The present invention discloses device that can generate a strong vortex in the vortex chamber which significantly enhances rate of reactions and effectiveness of waste water treatment. The present invention disclose vortex diodes with or without inserts/stabilizers as continuous flow reactors to induce cavitation to generate radicals which reduces Chemical Oxygen Demand (COD), ammoniacal nitrogen and color of waste water effectively in effluent treatments.

Vortex diodes as effluent treatment devices

Disclosed herein is a continuous tubular reactor based conversion of acetophenones to amino substituted acetophenones wherein the nitration is carried out at &#x2212;10 to 10&#xb0; C. followed by reduction to m-nitrophenone resulting in uniform output of product, said process comprising the steps of: a) Nitrating acetophenone with nitrating agent (nitration mixture or fuming nitric acid) at &#x2212;10 to 10&#xb0; C.; b) Isolating m-nitro acetophenone from a mixture of o and m-nitro acetophenone and c) Reducing the m-nitro to obtain m-amino acetophenone.

Continuous two step flow synthesis of M-amino acetophenone

A fractal impeller design for stirred tank reactors comprising plurality of main branches, each of which further having plurality of sub-branches with each sub branch having plurality of blades to distribute/dissipate energy in uniform manner and to achieve uniform temperature throughout the reactor while operating it at lower impeller speed to avoid high shear zones; wherein, the angular distances covered by the blades vary and yield variation in the local blade passage velocity for a given impeller rotation speed.

Growing community of inventors

Maharashtra, India

Amol Arvind Kulkarni