Praxair Technology, Inc.

Other

Amitabh Gupta

Shrikar Chakravarti

Ying Zhou

Balazs Hunek

Nigel Grinter

Alan T Y Cheng

Richard A Novak

Malcolm E Fabiyi

Robert Rex Sever

Ranko Bursac

Carl Joseph Heim

Dry ice shippers with unique structural features designed to deliver optimized performance for preserving one or more perishable items in a presence of dry ice during transport are provided. The improved dry ice shippers exhibit superior properties that overcome the performance limitations of conventional dry ice shippers.

Dry ice containing shippers

A bioreactor with an upward flowing impeller system for controlling a mammalian cell culture process is provided. The disclosed system enables control of the cell culture process by controlling the level of dissolved carbon dioxide in the cell culture media and prevent increases in the osmolality level is achieved by enhanced stripping of carbon dioxide via surface gas exchange with little or no damage to the mammalian cells. The use of an upward flow impeller combined with vertical baffles converts the swirling motions of the cell culture media into a largely vertical flow and promotes the removal of dissolved carbon dioxide via surface gas exchange with a sweep gas flowing over the top surface of the cell culture media within the bioreactor vessel.

Bioreactor with upward flowing impeller system for use in a mammalian cell culture process

A system and method for controlling a mammalian cell culture process are provided. Such control of the cell culture process involves control of the level of dissolved carbon dioxide in the cell culture media and the resulting ability to prevent increases in the osmolality level is achieved by enhanced stripping of carbon dioxide with little or no damage to the mammalian cells. The disclosed methods and systems of dissolved carbon dioxide stripping include enhanced surface gas exchange mechanisms within the bioreactor vessel through the use of an upward flow impeller combined with vertical baffles to convert swirling motions of the liquid into a largely vertical flow.

System and method for controlling a mammalian cell culture process

Methods for controlling the level of dissolved carbon dioxide and limiting osmolality in a mammalian cell culture process to enhance cell growth, viability and density, and increase biologic product concentration and yield are provided. Such control of the level of dissolved carbon dioxide and pH as well as the resulting ability to limit osmolality in a mammalian cell culture process is achieved by adopting alternative pH control strategies and COstripping techniques during a mammalian cell culture process. Such pH control techniques and carbon dioxide stripping occur without foam and with little or no damage to the mammalian cells.

Method for controlling pH, osmolality and dissolved carbon dioxide levels in a mammalian cell culture process to enhance cell viability and biologic product yield

An activated sludge wastewater treatment method is provided. The disclosed method includes: receiving a stream of wastewater into a mixed liquor in an uncovered activated sludge basin; introducing high purity oxygen to the mixed liquor in the activated sludge basin to produce euoxic conditions (i.e. a dissolved oxygen level in the range of between about 5 mg to 15 mg) in the activated sludge basin; passing a portion of the mixed liquor in the activated sludge basin through a clarifier to separate activated sludge and produce an effluent stream and an activated sludge stream; and recycling a portion of the activated sludge stream to the activated sludge basin to produce a mixed liquor having a solids loading of between about 3000 mg and about 10000 mg of suspended solids per liter of mixed liquor and a solids retention time of between about 7 days and 40 days.

Method for activated sludge wastewater treatment with high dissolved oxygen levels

An activated sludge wastewater treatment system is provided. The disclosed system includes: an uncovered activated sludge basin; a high purity oxygen aeration system; a secondary clarifier; a return activated sludge line and a waste activated sludge line; wherein the system operates at a solids loading of between about 3000 mg and about 10000 mg of suspended solids per liter of mixed liquor; a dissolved oxygen level in the aeration basin in the range of between about 5 mg to 15 mg; and a solids retention time of between about 7 days and 40 days.

System for activated sludge wastewater treatment with high dissolved oxygen levels

Disclosed are a carbon dioxide purification process and apparatus including (i) an adsorbing step for removing a predetermined amount of hydrocarbons from a carbon dioxide feed gas to reduce the caloric value of the feed stream, and (ii) a catalytic oxidation step located downstream of the adsorbing step for removing residual hydrocarbons from the feed gas by catalytic oxidation.

Method and apparatus for purifying carbon dioxide feed streams

A system for recovering absorbate such as carbon dioxide from an oxygen containing mixture wherein carbon dioxide is concentrated in an alkanolamine containing absorption fluid, oxygen is separated from the absorption fluid, the resulting fluid is heated, and carbon dioxide is steam stripped from the absorption fluid and recovered.

Carbon dioxide recovery plant

Carbon dioxide is recovered from a feed stream whose pressure is up to 30 psia by preferentially absorbing carbon dioxide from said feed stream into a liquid absorbent fluid, pressurizing and heating the resulting stream to a pressure sufficient to enable the stream to reach the top of the stripper at a pressure of 35 psia or greater, and stripping carbon dioxide from said stream in a stripper operating at a pressure of 35 psia or greater and recovering from said stripper a gaseous carbon dioxide product stream having a pressure of 35 psia or greater.

Carbon dioxide recovery at high pressure

A process for recovering carbon dioxide from a gas containing both carbon dioxide and oxygen wherein a carbon dioxide and oxygen containing gas is first contacted with an alkanolamine solution to produce an alkanolamine loaded with carbon dioxide and oxygen, the oxygen is separated from the absorption solution, such as by stripping with a scavenging gas, such as the carbon dioxide containing fluid obtained from the separation of carbon dioxide from the alkanolamine solution or nitrogen, prior to any heating of the absorption solution, and carbon dioxide is steam stripped from the absorption solution and recovered. By stripping the oxygen out of the alkanolamine solution, oxidative degradation of the alkanolamine can be reduced.

Carbon dioxide recovery from an oxygen containing mixture

A method for recovering carbon dioxide by absorption of carbon dioxide from a gas stream into a composite recovery solvent comprising preferably a lesser concentration of one or more fast reaction rate amines and a greater concentration of one or more slow reaction rate amines.

Carbon dioxide recovery with composite amine blends

A system for recovering absorbate such as carbon dioxide using an alkanolamine absorbent fluid, wherein the loaded absorbent is heated in a two step heating procedure prior to the separation of the absorbate from the absorbent, and wherein the loaded absorbent is deoxygenated after the first heating step and prior to the second heating step.

Growing community of inventors

Naperville, IL, United States of America

Amitabh Gupta