University of Illinois

Sandia Corporation

Washington University

The Penn State Research Foundation

Amit V Desai

Paul J A Kenis

Tobias Daniel Wheeler

Dexing Zeng

Christopher Alan Apblett

Joshua D Tice

David E Reichert

Amanul Haque

Thomas A Bassett

Birce C Önal

An electrostatic actuator is provide that can include a fluidic line, a first electrode, and a second electrode such that a gate chamber portion of the fluidic line is sandwiched between the first electrode and the second electrode. The electrostatic actuator can also include a pressure-balancing channel in fluid communication with the gate chamber portion where the first electrode is sandwiched between the pressure-balancing channel and the gate chamber portion. A pneumatic valve system is provided which includes an electrostatic gate and a fluidic channel fluidly separate from a fluidic control line. A pneumatic valve portion of the fluidic control line can be positioned relative to a portion of the fluidic channel such that expansion of the pneumatic valve portion restricts fluid flow through the fluidic channel. Methods of using an electrostatic actuator and a pneumatic valve system are also provided.

Microfluidic pressure amplifier circuits and electrostatic gates for pneumatic microsystems

A microreactor for preparing a radiolabeled complex or a biomolecule conjugate comprises a microchannel for fluid flow, where the microchannel comprises a mixing portion comprising one or more passive mixing elements, and a reservoir for incubating a mixed fluid. The reservoir is in fluid communication with the microchannel and is disposed downstream of the mixing portion. A method of preparing a radiolabeled complex includes flowing a radiometal solution comprising a metallic radionuclide through a downstream mixing portion of a microchannel, where the downstream mixing portion includes one or more passive mixing elements, and flowing a ligand solution comprising a bifunctional chelator through the downstream mixing portion. The ligand solution and the radiometal solution are passively mixed while in the downstream mixing portion to initiate a chelation reaction between the metallic radionuclide and the bifunctional chelator. The chelation reaction is completed to form a radiolabeled complex.

Microreactor and method for preparing a radiolabeled complex or a biomolecule conjugate

A vigilance monitoring system to determine the alertness of a driver of a vehicle. The system uses one or multiple sensors located at the driver-vehicle interface (steering wheel, accelerator, brakes). The sensor monitors the magnitude and frequency of the force (or displacement) exerted by a driver at the driver interface. A time derivative of the force or displacement profile is created. The variability of the time derivative of the force/displacement data from the general trend of the data as obtained by an optimized moving average of the data. An intelligent control system measures the variability and compares with an alertness rating scale to determine the alertness score of the driver and issue warning signals and actions as appropriate.

Vigilance monitoring technique for vehicle operators

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Urbana, IL, United States of America

Amit V Desai