Siemens Healthcare Gmbh

Emory University

Amit Saindane

Xiaodong Zhong

John N Oshinski

Deqiang Qiu

Embodiments relate to acquiring magnetic resonance (MR) images with suppressed residual blood signal in the early cardiac phases, leading to images with a preferred dark-blood appearance throughout the entire cardiac cycle, which improves accuracy of subsequent post-processing algorithms. The acquisition of the desired blood suppressed tissue images is achieved through a double inversion recovery pulse in DENSE sequences. The double inversion recovery pulse is applied after an electrocardiogram (ECG) trigger at a beginning point of a repetition time period, followed by a displacement encoding module at an inversion time during the repetition time period and a readout module comprised of a plurality of frames during a remainder of the repetition time period. The displacement encoding module applies a labelling process on the tissue, while the readout module applies an un-labelling process. The readout module comprises an imaging sequence adapted to acquire DENSE images.

Magnetic resonance method and apparatus for quantitative time-resolved assessment of tissue displacement and related biomarker parameters with blood suppression in the whole cardiac cycle

Embodiments relate to a magnetic resonance imaging (MRI) technique in which the two-dimensional (2D) Displacement Encoding with Stimulated Echoes (DENSE) imaging technique and the multiband technique are combined to provide a 2D multi-slice quantitative assessment of displacement, deformation, and mechanics indices of tissue. The scan time is equivalent to the short scan time of the conventional single slice 2D imaging while providing spatial volumetric coverage similar to three-dimensional (3D) imaging. The techniques are combined in both the sequence (i.e., data acquisition) and reconstruction sides. Quantification of tissue displacement and motion is achieved through the combination and further evaluation of tissue mechanical properties is provided by calculating different indices based on the displacement and motion values.

Magnetic resonance method and apparatus for quantitative simultaneous multi-slice assessment of tissue displacement, deformation, and related biomarker parameters

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Decatur, GA, United States of America

Amit Saindane