University of California

University of Delaware

Amit Kumar Jha

Kevin Edward Healy

Mary C Farach-Carson

Wesley M Jackson

Andrew Boyle

Xinqiao Jia

Eda Isil Altiok

Yerem Yeghiazarians

Andreas Stahl

Judith Kraiczy

Catherine E Safran

Padma P Srinivasan

Jianqin Ye

Kevin Tharp

The present disclosure provides compositions comprising a hydrogel and a cell adhesion ligand that enhances the differentiation of mesenchymal stem cells into brown adipocytes, and/or enhances the maintenance of brown adipocytes. In some cases, a subject composition includes cells that are embedded within the hydrogel. The present disclosure also provides methods of making and using the subject compositions.

Compositions and methods for producing and administering brown adipocytes

The present disclosure provides methods for sulfonation of hyaluronic acid. The present disclosure provides sulfonated hyaluronic acid, and compositions, including pharmaceutical compositions, comprising the sulfonated hyaluronic acid. The present disclosure provides implantable materials and drug delivery compositions comprising a subject sulfonated hyaluronic acid.

Ethylsulfonated hyaluronic acid biopolymers and methods of use thereof

Provided herein are hydrogel cell matrices, hydrogel cell matrix systems for the support, growth, and differentiation of a stem cell or progenitor cell and methods for making such hydrogel cell matrices.

Growth factor sequestering and presenting hydrogels

A method for enhancing chondrogenesis in a subject in need thereof comprises administering to the subject an effective amount of a pharmaceutical composition comprising a growth factor bound to hyaluronic acid (HA)-based hydrogel particles (HGPs). The hyaluronic acid (HA)-based hydrogel particles (HGPs) are conjugated with a heparan sulfate proteoglycan (HSPG). Related medicaments and methods for preparing the medicaments are provided.

Injectable delivery system for heparan-binding growth factors

Provided herein are compositions and methods for isolating and culturing cardiac progenitor cells, and for improved transplantation.

Cardiosphere derived cell population and methods of use

Growing community of inventors

Oakland, CA, United States of America

Amit Kumar Jha