Council of Scientific and Industrial Research

Fdc Limited

Amit Chandrakant Tawte

Subhash Prataprao Chavan

Mohan Anand Chandavarkar

Hanumant Bapurao Borate

Deepali Damodar Rao

Ramkrishnan Ramachandran Iyer

Sangmeshwer Prabhakar Sawargave

Suleman Riyajsaheb Maujan

Sunita Sharad Kunte

Sangeshwer Prabhakar Sawargave

Ramkrishnan Ramachaandran Iyer

Sangmeshwer Prabhkara Sawargave

Gajanan Jalindar Chavan

Vikas Vasant Nawathye

Ramakrishnan Ramacahndran Iyer

Ananda Shahaji Kudale

Hanumat Bapurao Borate

Disclosed herein are novel antifungal compounds of Formula 1, containing 1-substituted, 4-(substituted phenoxy-methyl)-1,2,3-triazole moieties coupled to a core having triazole ring, (un)substituted phenyl ring and tertiary alcoholic functionality, and pharmaceutically acceptable salts thereof; methods for preparing these compounds; and pharmaceutical preparations containing these novel compounds for prevention and treatment of fungal infections. 

1-substituted, 4-(substituted phenoxymethyl)-1,2,3-triazole compounds with antifungal properties and methods for preparation thereof

Disclosed herein are novel antifungal compounds of Formula 1, containing fluconazole pharmacophore moieties coupled with other moieties including aryl enones and chalcones and pharmaceutically acceptable salts thereof, methods for preparing these compounds and pharmaceutical preparations containing these novel compounds for prevention and treatment of fungal infections. 

Hybrid molecules containing pharmacophores of fluconazole as antifungal agents and their preparation

The invention discloses optically active compounds of Formula (1a) or Formula (1b), 

Optically active fluconazole analogues containing thiophenes as antifungal agents

The present invention discloses novel enantiomeric antifungal compounds of Formula (1a) and Formula (1b) containing thieno-[2,3-d]Jpyrimidin-4(3H)-one moiety and pharmaceutically acceptable salts thereof, method of preparing these compounds, the use of these compounds in prevention and treatment of fungal infections, and pharmaceutical preparations containing these compounds. 

Enantiomers of fluconazole analogues containing thieno-[2,-3-D]pyrimidin-4(3H)-one moiety as antifungal agents

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Mumbai, India

Amit Chandrakant Tawte