Rmx, LLC

Precision Biopsy, Inc.

Biotectix LLC

Cardiac Pacemakers, Inc.

University of Colorado

Amir J Tehrani

David Ligon

Rose Province

Chang Y Lee

Amy Michelle Goodman

Edward A Jasion

Sarah M Richardson-Burns

Jeffrey L Hendricks

Bruce H KenKnight

Eric G Lovett

Adam W Cates

Drew Hoffmann

Alan Richard Schwartz

Priya N Werahera

David Hillman

Peter Eastwood

Devices and methods are provided to treat acute and chronic heart failure by using one or more implantable or non-implantable sensors along with phrenic nerve stimulation to reduce intrathoracic pressure and thereby reduce pulmonary artery, atrial, and ventricular pressures leading to reduced complications and hospitalization.

Devices and methods for reducing intrathoracic pressure

A device and method for treating a variety of conditions, disorders or diseases with diaphragm/phrenic nerve stimulation is provided.

Airway diagnostics utilizing phrenic nerve stimulation device and method

A method of evaluating an image indicating a potential presence of a cancer lesion at a location within a prostate of a patient by transmitting light from an optical probe toward a location, receiving fluorescence spectra by the optical probe from the location, and generating a visual display of a diagnosis classification so as to confirm or contradict the existence of the cancer lesion at the location.

Diagnosis and treatment of tissue

A system and method for testing tissue in a patient. An optical probe illuminating the tissue generates reflected light corresponding to the illuminated tissue. A spectrometer and a tissue classification system provide a diagnostic classification. A treatment device delivers treatment to the tissue while the probe is in position to sense the reflected light.

A system, method, and storage device storing computer executable instructions for use in tissue analysis and therapy. A motorized optical probe for illuminating tissue generates light fluorescence and/or diffuse reflectance signals corresponding to the illuminated tissue. One or more ultrasound, CT and MRI imaging guidance systems identify the position of the optical probes relative to the tissue. An imaging system generates a three-dimensional image of the tissue based on the generated light signals and the identified position of the optical probe.

Motorized optical imaging of prostate cancer

A system, method, and storage device storing computer executable instructions for use in tissue analysis and therapy. An optical probe array has at least two or more optical probes for illuminating tissue and generates light fluorescence and/or diffuse reflectance signals corresponding to the illuminated tissue. One or more ultrasound, CT and MRI imaging guidance systems identify the position of the optical probes relative to the tissue. The imaging guidance system can also be a fusion of an MRI or CT image provided by the MRI or CT imaging guidance system and an ultrasound image provided by the ultrasound imaging guidance system. An imaging system generates a three-dimensional image of the tissue based on the generated light signals and the identified position of the optical probes.

Three-dimensional optical imaging and therapy of prostate cancer

A device and method is provided for biasing lung volume by electrically stimulating tissue associated with the diaphragm or phrenic nerve at a low level.

Device for manipulating tidal volume and breathing entrainment

A device and method is provided for increasing the functional residual capacity of lungs of a subject by electrically stimulating tissue associated with the diaphragm or phrenic nerve of the subject.

Device and method for manipulating exhalation

An implantable medical lead connecting to a device header of a medical apparatus and having an electrode, a conductor, and a conductive polymer layer formed on at least a portion of the medical lead. An insulative sheath surrounds the conductive polymer layer for electrical insulation. The conductive polymer layer and insulative sheath maintain mechanical and electrical continuity of the lead in the event of fracture. The conductive polymer layer is composed of conductive polymers and may contain one or more dopants for improving electrical characteristics, mechanical characteristics, and processability.

Electrically conductive and mechanically supportive polymer materials for biomedical leads

Electrically conductive and mechanically supportive materials for biomedical leads

A method and device is provided for adding to breathing by stimulating tissue to elicit a diaphragm response during intrinsic breathing.

Device and method for adding to breathing

A device and method are provided for managing the treatment of a patient with respiratory disorders or symptoms. Respiratory parameters are sensed and recorded and communicated to an external device to provide information to a patient and/or provider for further treatment or diagnosis. Also respiratory disorders such as apnea or hypoventilation may be treated by electrically stimulating the diaphragm muscle or phrenic nerve in response to a sensed respiratory parameter or characteristic.

Breathing disorder detection and therapy delivery device and method

A device and method is provided for electrically stimulating the diaphragm to control breathing while inhibiting respiratory drive. A stimulation phase is identified. The stimulation phase is a period of time within the breathing cycle in which stimulation will inhibit respiratory drive. The respiratory drive inhibition may be used in a number of applications including but not limited to: improving or remodeling the heart in heart failure patients, treating apnea, chronic obstructive pulmonary disorder (COPD), and hypertension.

Growing community of inventors

San Francisco, CA, United States of America

Amir J Tehrani