Bsp Biological Signal Processing Ltd.

Amir Beker

Tamir Ben-David

Orna Bregman-Amitai

Yair Granot

Eran Toledo

Assaf Hasson

Tamir Ben David

Alexander Zeltser

An implantable device for analyzing a high frequency (HF) electrogram signal received from subcutaneous, above-rib pickup locations, the device including an implantable electrode for use inside a living body, and a can for subcutaneous implantation, the can including a signal pickup configured to pick up an electrogram signal including a high frequency (HF) component, a signal filter connected to the signal pickup and configured to measure a high frequency (HF) component from the electrogram signal, and an analyzer for analyzing the HF component of the electrogram signal, wherein the analyzer is configured to analyze at least one time-varying parameter of the HF component of the electrogram signal, and the signal filter is configured to measure the electrogram signal by using a signal picked up from at least two pickup locations which are both subcutaneous and above-rib. Related apparatus and methods are also described.

Detection and monitoring using high frequency electrogram analysis

An implantable device for analyzing a high frequency (HF) electrogram signal including an implantable electrode, a signal pickup configured to pick up an electrogram signal including a HF component, a signal filter connected to the signal pickup and configured to measure a HF component from the signal only during a specific portion of a cardiac cycle, and an analyzer for analyzing the HF component, wherein the signal pickup, the signal filter and the analyzer are included within an implantable container, and the analyzer is configured to analyze at least one time-varying parameter of the HF component, and the signal filter is configured to measure the signal by using a signal picked up from at least one electrode selected from a group consisting of (a) intracardiac, (b) subcutaneous, (c) a can of the implanted device, (d) a combination of two of the above. Related apparatus and methods are also described.

A method for analyzing a high frequency (HF) electrogram signal including (a) providing at least one electrogram signal from an electrode located within a subject's body, (b) measuring the electrogram signal at a high frequency during a specific segment of a cardiac cycle, generating a HF electrogram signal, and (c) having a computer measure at least one time-varying parameter of the HF electrogram signal. Related apparatus and methods are also described.

Detecting cardiac ischemia by detecting local changes in high frequency ECG parameters. Local changes may be, for example, local reduction in RMS of high frequency components, for example, during a stress test.

Apparatus and method for identifying myocardial ischemia using analysis of high frequency QRS potentials

An apparatus for QRS waveform quantifying, comprising: an input unit, for receiving one or more high frequency (HF) range QRS complexes from one or more ECG leads, a primary analyzer, for calculating a primary index from the high frequency (HF) range QRS complex, and a secondary analyzer, connected after the primary analyzer, for deriving a secondary index from the primary index, thereby to provide a quantification of QRS complexes.

Apparatus and method for analysis of high frequency QRS complexes

Apparatus for graphically representing a substantially periodic signal having substantially periodic segments, comprising a graphic transformer for converting the periodic segments into encodings respectively for arrangement in a first dimension and successively indexing the encodings to form a two-dimensional coded image, thereby to represent, within the image, dynamic changes of the periodic segments over the signal.

Apparatus and method for efficient representation of periodic and nearly periodic signals for analysis

A device for reducing noise in signals having successive substantially repetitive portions, comprising: an iterative averager operative to superimpose and average said substantially repetitive portions to produce a running average thereof, and an iteration ender comprising a noise analyzer for determining a noise level in said running average and ending operation of said iterative averager when said noise level reaches a predetermined level. Also, a method of obtaining an indication of ischemia in a patient using an ECG signal therefrom, the method comprising: extracting an ECG signal over a duration, extracting from said ECG signal a series of QRS complexes over said duration, extracting high frequency components of said QRS complexes, analyzing said high frequency components over said duration for at least one of a predetermined quality, and inferring from said predetermined quality an indication of ischemia.

Growing community of inventors

Rosh-Ha′ayin, Israel

Amir Beker