Covestro Deutschland Ag

Bayer Intellectual Property Gmbh

Covestro Intellectual Property Gmbh & Co. Kg

Amgad Salah Moussa

Gernot Jäger

Thomas Hamedinger

Swantje Behnken

Giulio Lolli

Guenter Olf

Peter Lehner

Gernot Jaeger

Bastian Mahr

Wolf Kloeckner

Jorgen Magnus

Bernd Pennemann

Michael Merkel

Knut Sommer

Wolfgang Beckmann

Guido Becker

Gernot Jager

Günter Olf

Ivonne Görtz

Jung-Won Youn

Georg Sprenger

Mohammad Yalfani

Simon Klaffl

Andreas Damm

Hasan Akyildiz

Gunter Olf

Gernot JÄGER

The invention relates to a method for producing aminobenzoic acid or a aminobenzoic acid derivative via the fermentation of a suitable raw material under the influence of suitable microorganisms and obtaining a fermentation broth containing aminobenzoate and/or aminobenzoic acid. In particular, the invention relates to the step of obtaining the aminobenzoic acid from the fermentation broth, wherein the crystallisation of aminobenzoic acid is carried out via a simple one-stage acid treatment in the presence of seed crystals. The aminobenzoic acid crystallised in this simple manner can be easily separated from the mother liquor, further cleaned if necessary, and then supplied to the different applications.

Method for producing aminobenzoic acid or an aminobenzoic acid derivative

The present invention relates to the production of o-aminobenzoic acid from fermentable substrates using yeast cells.

Process for the production of ortho-aminobenzoic acid and/or aniline from fermentable substrate using recombinant yeast

The present invention relates to a process for preparing aminobenzoic acid or an aminobenzoic acid conversion product, comprising the steps of: (I) providing an aqueous solution of aminobenzoic acid using a fermentation process; (II) adsorbing aminobenzoic acid; (III) desorbing aminobenzoic acid at a pH in the range from &#x2212;0.8 to 3.0, preferably &#x2212;0.5 to 3.0, more preferably 0.1 to 3.0, very preferably 0.5 to 2.5, very exceptionally preferably 1.0 to 2.0; (IV) obtaining the aminobenzoic acid from the desorbate obtained in step (III); (V) optionally further converting the aminobenzoic acid obtained in step (IV) to an aminobenzoic acid conversion product.

Process for preparing aminobenzoic acid or an aminobenzoic acid conversion product

The invention provides a recombinant microbial host cell capable of converting a raw material comprising a fermentable carbon substrate to o-aminobenzoate biologically. The invention further provides a method for producing aniline, comprising the steps of: a) producing o-aminobenzoate by fermentation of a raw material comprising at least one fermentable carbon substrate using the recombinant microbial host cell of the capable of converting said raw material comprising at least one fermentable carbon substrate to o-aminobenzoate biologically, wherein said o-aminobenzoate comprises anthranilate anion, b) converting said o-aminobenzoate from said anthranilate anion to anthranilic acid by acid protonation, c) recovering said anthranilic acid by precipitation or by dissolving in an organic solvent, and d) converting said anthranilic acid to aniline by thermal decarboxylation in an organic solvent.

Recombinant strain producing O-aminobenzoate and fermentative production of aniline from renewable resources via 2-aminobenzoic acid

The invention relates to a method for producing aniline or products that are obtained by further chemical reaction of aniline (aniline derivatives), involving decarboxylation of aminobenzoic acid, particularly ortho-aminobenzoic acid, in which one portion of the previously formed crude aniline is recirculated in the decarboxylation step. The aminobenzoic acid is obtained enzymatically or chemically, preferably enzymatically.

Method for producing aniline or an aniline conversion product

The invention relates to a method for producing aniline, comprising the steps of: a) providing o-aminobenzoate, wherein said o-aminobenzoate comprises anthranilate anion and a suitable cation, b) converting said anthranilate anion to aniline by thermal decarboxylation in the presence or absence of a catalyst, c) extracting the aniline produced in step b) in an organic solvent at least once, and d) purifying the aniline produced in steps b) and c) by distillation, wherein said distillation produces aniline and a water phase.

Production of aniline via anthranilate

The invention relates to an industrial-scale method for the vapor-phase hydrogenation of dinitrotoluene (DNT). According to said method, a stream containing DNT is sprayed into a carrier-gas stream containing hydrogen, optionally in the presence of an atomizing gas, unevaporated liquid droplets are extracted from the substantially gaseous stream that is obtained and the resultant gas stream is catalytically hydrogenated to form diaminotoluene.

Method for producing diaminotoluene

The present invention relates to a process for the purification of aniline which originates from gas phase hydrogenations. In this process, only a minimum proportion of the aniline has to be evaporated and condensed again. The process is highly efficient in removing compounds which have phenolic hydroxyl groups and results in minimal losses of aniline. This process also reduces the unwanted coupling mechanisms in the division of the overall crude product in the fraction condensation into individual substreams and the subsequent workup of these.

Process for the purification of aniline from gas phase hydrogenations

The invention relates to a process for purifying aniline produced by gas-phase hydrogenation of nitrobenzene, by fractional condensation of the crude reaction product obtained in gaseous form so that at least two liquid process products, a partial condensate (PK) and a total condensate (TK), are obtained.

Process for purifying aniline from gas phase hydrogenations

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Cologne, Germany

Amgad Salah Moussa