Amoco Corporation

Amelia Buharin

David J Lane

Jyotsna S Shah

William G Weisburg

Jing Liu

The invention features nucleic acid probes and methods for detecting Pneumocystis carinii (e.g., human or ferret P. carinii) in hybridization assays.

Nucleic acid probes and methods for detecting Pneumocystis carinii

The present invention relates to a method of selectively detecting Giardia lamblia in a sample. The method makes use of at least one nucleic acid probe which is a DNA or PNA sequence which hybridizes, under appropriate conditions, to the ribosomal RNA or the ribosomal DNA of Giardia lamblia but does not hybridize to the ribosomal RNA or the ribosomal DNA of other organisms (non-Giardia lamblia organisms) which may be present in a sample.

Nucleic acid probes for the detection of Giardia lamblia

Nucleic acid probes capable of hybridizing to rRNA or rDNA of Pneumocystis carinii and not to rRNA or rDNA of non-Pneumocystis are described along with methods utilizing such probes for the detection of Pneumocystis carinii in clinical samples.

Nucleic acid probes for the detection of Pneumocystis carinii

Nucleic acid probes capable of hybridizing to rRNA of eubacteria and not to rRNA of non-eubacteria are described along with methods utilizing such probes for the detection of eubacteria in clinical and other samples. Preferred embodiments include probes capable of distinguishing between gram-positive and gram-negative bacteria.

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Roslindale, MA, United States of America

Amelia Buharin