Wake Forest University

Amber N Weissenfluh

Mark E Welker

Surya Raj Banks

Emmanuel C Opara

Aleksander Skardal

Described herein are compounds having a hydrogen-bonding group and optionally a functional group for binding (e.g., covalently binding) the compound to another compound (e.g., hyaluronic acid and/or gelatin). A compound of the present invention may have a structure represented by and/or comprising Formula I, Formula II, Formula III, Formula IV, Formula IV', Formula V, Formula V&#x2032;, Formula VI, Formula VII, and/or Formula VIII as described herein. Compositions including compounds of the present invention along with methods of preparing and using the same are also described herein.

Hydrogen-bonding compounds, compositions comprising the same, and methods of preparing and using the same

Modified alginates are described herein along with hydrogels comprising the same. A modified alginate may be prepared by reacting alginate and an aromatic compound (e.g., an aromatic amine) and/or pH sensitive compound. The modified alginates, hydrogels, and/or methods described herein may be used to coat and/or encapsulate at least a portion of a bioactive substance, optionally for oral delivery in humans and other animals.

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Lemon Grove, CA, United States of America

Amber N Weissenfluh