Gen-probe, Inc.

Amber Hillius

Ankur Shah

Mehrdad R Majlessi

Daniel Kolk

Pamela Douglass

Paul M Darby

Jo Ann Jackson

Siobhan Miick

Marcela Alejandra Carvallo Pinto

Hee Cheol Kim

Disclosed are oligonucleotides, oligonucleotide compositions, kits, methods, formulations, and reaction mixtures that provide for sensitive and specific detection of a target nucleic acid sequence, or amplicon generated from a target nucleic acid sequence, of Varicella-Zoster Virus (VZV1 (if present) in a sample. The oligonucleotides, compositions, kits, methods, formulations, and reaction mixtures can be used to detect the presence of VZV in a sample. The oligonucleotides, compositions, kits, methods, formulations, and reaction mixtures can also be used to amplify specific target nucleic acid regions of VZV.

Compositions and methods for amplifying or detecting varicella-zoster virus

The disclosed disclosure is related to methods, compositions, and kits for targeting Adenovirus, Metapneumovirus, and/or Rhinovirus nucleic acid. Compositions include amplification oligomers and/or detection probe oligomers. Kits and methods comprise at least one of these oligomers. Methods include uniplex and multiplex amplification and detection reactions.

Compositions and methods to detect adenovirus nucleic acids and metapneumovirus and/or rhinovirus nucleic acids

Oligomer nucleotides, compositions, methods, kits, and uses are provided for detecting or quantifying a Human Cytomegalovirus virus 1 (CMV (human herpesvirus 5, HHV5) nucleic acid, e.g., using nucleic acid amplification and hybridization assays. Multiphase amplification of a CMV target sequence is also described. The oligomer nucleotides, compositions, methods, kits, and uses can be used to amplify and/or detect the UL56 gene of CMV.

Compositions and methods for amplifying, detecting or quantifying human cytomegalovirus

The disclosure is related to compositions, for targeting Adenovirus nucleic acid. Compositions include amplification oligomers and/or detection probe oligomers.

Compositions to detect adenovirus nucleic acids

The disclosed disclosure is related to methods, compositions, and kits for targeting Rhinovirus nucleic acid. Compositions include amplification oligomers and/or detection probe oligomers. Kits and methods comprise at least one of these oligomers. Methods include uniplex and multiplex amplification and detection reactions.

Methods to detect rhinovirus nucleic acids

The disclosed disclosure is related to methods, compositions, and kits for targeting Adenovirus, nucleic acid. Compositions include amplification oligomers and/or detection probe oligomers. Kits and methods comprise at least one of these oligomers. Methods include uniplex and multiplex amplification and detection reactions.

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San Diego, CA, United States of America

Amber Hillius